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The impact of using sagittal abdominal diameter to predict major cardiovascular events in European patients with type 2 diabetes
Linköping University, Department of Medical and Health Sciences, Division of Community Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in West Östergötland, "Primary Health Care in Motala".
Linköping University, Department of Medical and Health Sciences, Division of Community Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in West Östergötland, "Primary Health Care in Motala".
Linköping University, Department of Medical and Health Sciences, Division of Community Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in West Östergötland, "Primary Health Care in Motala".
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Heart and Medicine Center, Department of Thoracic and Vascular Surgery.ORCID iD: 0000-0002-9095-403X
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2017 (English)In: NMCD. Nutrition Metabolism and Cardiovascular Diseases, ISSN 0939-4753, E-ISSN 1590-3729, Vol. 27, no 5, 418-422 p.Article in journal (Refereed) Published
Abstract [en]

Background and aims: Obesity is associated with diabetes type 2 and one of the most important risk factors for cardiovascular disease. We explored if sagittal abdominal diameter (SAD) is a better predictor of major cardiovascular events than waist circumference (WC) and body mass index (BMI) in type 2 diabetes. Methods and results: The CARDIPP study consists of a cohort of patients with type 2 diabetes. In this study we used data from 635 participants with no previous myocardial infarction or stroke, with a mean follow-up time of 7.1 years. SAD, WC and BMI were measured at baseline and the end-point was first cardiovascular event, measured as a composite of ICD-10 codes for acute myocardial infarction, stroke or cardiovascular mortality. SAD was significantly higher in the major cardiovascular event group compared to participants that did not suffer a major cardiovascular event during follow-up (p amp;lt; 0.001). SAD amp;gt; 25 cm was the only anthropometric measurement that remained associated with major cardiovascular events when adjusted for modifiable and non-modifiable factors (hazard ratio 2.81, 95% confidence interval 1.37-5.76, p = 0.005). Conclusion: SAD with the cut off level of amp;gt; 25 cm, if confirmed in larger studies, may be used as a more independent risk-assessment tool compared with WC in clinical practice, to identify persons with type 2 diabetes at high cardiovascular risk. (C) 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Place, publisher, year, edition, pages
ELSEVIER SCI LTD , 2017. Vol. 27, no 5, 418-422 p.
Keyword [en]
Diabetes; Obesity; Anthropometric measurements; Cardiovascular risk
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:liu:diva-139300DOI: 10.1016/j.numecd.2017.02.001ISI: 000403554000006PubMedID: 28390663OAI: oai:DiVA.org:liu-139300DiVA: diva2:1120906
Note

Funding Agencies|Medical Research Council of Southeast Sweden; Center for Medical Image Science and Visualization (CMIV)), Linkoping University; Futurum; King Gustaf V and Queen Victoria Freemason Foundation; GE Healthcare

Available from: 2017-07-07 Created: 2017-07-07 Last updated: 2017-07-07

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Rådholm, KarinTengblad, AndersDahlén, ElsaLänne, TosteEngvall, JanNyström, Fredrik HÖstgren, Carl Johan
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Division of Community MedicineFaculty of Medicine and Health Sciences"Primary Health Care in Motala"Division of Cardiovascular MedicineDepartment of Thoracic and Vascular SurgeryDepartment of Clinical Physiology in LinköpingDepartment of Endocrinology
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NMCD. Nutrition Metabolism and Cardiovascular Diseases
Cardiac and Cardiovascular Systems

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