liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Population-based study showed that necrotising enterocolitis occurred in space-time clusters with a decreasing secular trend in Sweden
University of Gothenburg, Sweden.
Linköping University, Department of Medical and Health Sciences, Division of Radiological Sciences. Linköping University, Faculty of Medicine and Health Sciences. University of Gothenburg, Sweden.
University of Gothenburg, Sweden.
University of Gothenburg, Sweden.
Show others and affiliations
2017 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 106, no 7, 1097-1102 p.Article in journal (Refereed) Published
Abstract [en]

Aim: This study investigated space-time clustering of neonatal necrotising enterocolitis over three decades. Methods: Space-time clustering analyses objects that are grouped by a specific place and time. The Knox test and Kulldorffs scan statistic were used to analyse space-time clusters in 808 children diagnosed with necrotising enterocolitis in a national cohort of 2 389 681 children born between 1987 and 2009 in Sweden. The municipality the mother lived in and the delivery hospital defined closeness in space and the time between when the cases were born - seven, 14 and 21 days - defined closeness in time. Results: The Knox test showed no indication of space-time clustering at the residential level, but clear indications at the hospital level in all the time windows: seven days (p = 0.026), 14 days (p = 0.010) and 21 days (p = 0.004). Significant clustering at the hospital level was found during 1987-1997, but not during 1998-2009. Kulldorffs scan statistic found seven significant clusters at the hospital level. Conclusion: Space-time clustering was found at the hospital but not residential level, suggesting a contagious environmental effect after delivery, but not in the prenatal period. The decrease in clustering over time may reflect improved routines to minimise the risk of contagion between patients receiving neonatal care.

Place, publisher, year, edition, pages
WILEY , 2017. Vol. 106, no 7, 1097-1102 p.
Keyword [en]
Cluster analysis; Necrotising enterocolitis; Neonatal care; Precipitating contagion; Preterm infant
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:liu:diva-139608DOI: 10.1111/apa.13851ISI: 000405216700022PubMedID: 28349558OAI: oai:DiVA.org:liu-139608DiVA: diva2:1133755
Note

Funding Agencies|Swedish government; county councils

Available from: 2017-08-16 Created: 2017-08-16 Last updated: 2017-08-16

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Ahle, Margareta
By organisation
Division of Radiological SciencesFaculty of Medicine and Health Sciences
In the same journal
Acta Paediatrica
Pediatrics

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 52 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf