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A Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Barnafrid. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in Central Östergötland, Department of Child and Adolescent Psychiatry in Linköping.
Uppsala University, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
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2017 (English)In: Child Psychiatry and Human Development, ISSN 0009-398X, E-ISSN 1573-3327, Vol. 48, no 4, p. 584-596Article in journal (Refereed) Published
Abstract [en]

An increasing prevalence of mental health problems calls for more knowledge into factors associated with resilience. The present study used multiple statistical methodologies to examine a biopsychosocial model of risk and resilience on preadolescence behavior. Data from 889 children and mothers from a birth cohort were used. An adversity score was created by combining maternal symptoms of depression, psychosocial risk and childrens experiences of life events. The proposed resilience factors investigated were candidate genetic polymorphisms, child temperament, social functioning, and maternal sense of coherence. The l/ l genotype of the serotonin transporter linked polymorphic region was associated with lower internalizing scores, but not mainly related to the level of adversity. An easy temperament was associated with resilience for children exposed to high adversity. Social functioning was found to be promotive independent of the risk level. The results support a multiple-level model of resilience indicating effects, though small, of both biological and psychosocial factors.

Place, publisher, year, edition, pages
SPRINGER , 2017. Vol. 48, no 4, p. 584-596
Keywords [en]
Child; Genotype; Longitudinal; Mental health; Resilience
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:liu:diva-141129DOI: 10.1007/s10578-016-0684-xISI: 000410242400007PubMedID: 27628896OAI: oai:DiVA.org:liu-141129DiVA, id: diva2:1144752
Note

Funding Agencies|Swedish Council for Working Life and Social Research (FAS); Swedish Research Council (VR); Clas Groschinsky Memorial Foundation Stockholm; Hallsten Research Foundation; ALF; County Council of Ostergtland

Available from: 2017-09-27 Created: 2017-09-27 Last updated: 2017-10-24

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Agnafors, SaraSvedin, Carl GöranBladh, MarieSydsjö, Gunilla
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Division of Children's and Women's healthFaculty of Medicine and Health SciencesBarnafridDepartment of Child and Adolescent Psychiatry in LinköpingDepartment of Gynaecology and Obstetrics in Linköping
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Child Psychiatry and Human Development
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