liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Acute skin trauma induces hyperemia, but superficial papillary nutritive perfusion remains unchanged
Oslo University Hospital, Norway; University of Oslo, Norway.
Oslo University Hospital, Norway; University of Oslo, Norway.
Oslo University Hospital, Norway; Ostfold Hospital Trust, Norway.
Linköping University, Department of Biomedical Engineering, Division of Biomedical Engineering. Linköping University, Faculty of Science & Engineering.
Show others and affiliations
2017 (English)In: Microcirculation, ISSN 1073-9688, E-ISSN 1549-8719, Vol. 24, no 7, e12389Article in journal (Refereed) Published
Abstract [en]

Objectives: Superficial skin papillary capillaries with blood supply from a superficial vascular plexus and regulated by local metabolic needs supply oxygen and nutrients for epithelial cell proliferation. A deep vascular plexus regulated by autonomous nerves serves body thermoregulation. In healthy volunteers, we assessed circulatory effects of a standardized skin trauma by CAVM, DRS, and LDPM to assess the measuring depth of the three techniques and to describe the acute trauma effects on nutritive and thermoregulatory perfusion. Methods: Volunteers (n=12) were examined at baseline and after induction of a 5.0 mmx1.0 mm incision on the forearm; 30 minutes after the trauma induction, data were collected at 0-1, 2-3 and 30 mm distances. Results: LDPM showed hyperemia at 2-3 mm distance (35.8 +/- 15.2 a.u.), but not at 30 mm distance (7.4 +/- 2.5 a.u.) compared to baseline (8.8 +/- 1.8 a.u.). The DRS saturation increased at 2-3 mm (71.2 +/- 4.8%), but not at 30 mm (49.8 +/- 7.9%) compared to baseline (45.8 +/- 7.4%). Capillary density and flow velocities were unaffected at all distances. Conclusions: The results indicate that skin nutritive papillary capillary function can be assessed by CAVM and DRS, but not with LDPM because of its dependence of the deep plexus perfusion.

Place, publisher, year, edition, pages
WILEY , 2017. Vol. 24, no 7, e12389
Keyword [en]
computer assisted video microscopy; diffuse reflectance spectroscopy; laser Doppler perfusion measurements; microcirculation; skin trauma responses
National Category
Physiology
Identifiers
URN: urn:nbn:se:liu:diva-142161DOI: 10.1111/micc.12389ISI: 000412526700008PubMedID: 28632939OAI: oai:DiVA.org:liu-142161DiVA: diva2:1151570
Available from: 2017-10-23 Created: 2017-10-23 Last updated: 2017-10-23

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Salerud, Göran
By organisation
Division of Biomedical EngineeringFaculty of Science & Engineering
In the same journal
Microcirculation
Physiology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 80 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf