liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Emesis in patients receiving acupuncture, sham acupuncture or standard care during chemo-radiation: A randomized controlled study
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences.
2017 (English)In: Complementary Therapies in Medicine, ISSN 0965-2299, E-ISSN 1873-6963, Vol. 34, 16-25 p.Article in journal (Refereed) Published
Abstract [en]

Objective: To study nausea, vomiting and need for rescue antiemetics in patients receiving antiemetic acupuncture, sham acupuncture or standard care during concomitant chemotherapy during pelvic radiotherapy. Methods: In total, 68 patients participated (75% women, mean age 56 years, 53% had gynecological, 43% colorectal, and 4% other cancer types). Fifty-seven of them were blinded randomized to verum (n = 28) or sham (n = 29) acupuncture, median 10 sessions. During the study period of four weeks, the patients daily registered their nausea, vomiting and consumption of antiemetics. They were compared to a reference group (n = 11) receiving standard care only, who delivered these data once (after receiving mean 27 Gy radiotherapy dose). Results: More patients in the sham acupuncture group (17 of 20; 85%, p = 0.019, RR 1.81, CI 1.06-3.09) consumed antiemetics, compared to the verum acupuncture group (8 of 17; 47%). In the standard care group, 7 of 11 (63%) consumed antiemetics. The verum acupuncture treated patients experienced lower intensity of nausea than the other patients (p = 0.049). There was a non-significant tendency that more patients receiving either sham acupuncture or standard care experienced nausea (21 of 31; 68%) than patients receiving verum acupuncture (9 of 17; 53%: p = 0.074, RR 1.58, CI 0.91-2.74). Conclusion: Patients treated with verum acupuncture needed less antiemetics and experienced milder nausea than other patients. Our study was small and many analyses lacked statistical power to detect differences; we welcome further sham-controlled efficacy studies and studies regarding the role of non-specific treatment components for experiencing antiemetic effects of acupuncture.

Place, publisher, year, edition, pages
CHURCHILL LIVINGSTONE , 2017. Vol. 34, 16-25 p.
Keyword [en]
Acupuncture therapy; Complementary and alternative medicine; Nausea; Supportive care; Vomiting
National Category
Nursing
Identifiers
URN: urn:nbn:se:liu:diva-142155DOI: 10.1016/j.ctim.2017.07.003ISI: 000412611500003PubMedID: 28917369OAI: oai:DiVA.org:liu-142155DiVA: diva2:1151688
Note

Funding Agencies|Swedish Cancer Society [04 0483]; Swedish Institute for Health Sciences; Region of Ostergotland [LIO-4998, 2005-279-83, LIO-4762, LIO-7433, LIO-10456, LIO-20071]; University of Linkoping; Cancer Rehabilitation Foundation [C 40111]; Vardal Foundation-for Health Care Sciences and Allergy Research; Ostgota Cancer Fund; Osher Center for Integrative Medicine, Karolinska Institute

Available from: 2017-10-24 Created: 2017-10-24 Last updated: 2017-10-24

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Widgren, YlvaEnblom, Anna
By organisation
Division of PhysiotherapyFaculty of Medicine and Health Sciences
In the same journal
Complementary Therapies in Medicine
Nursing

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 75 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf