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Nuclease activity as a specific biomarker for breast cancer.
SOMAprobes S.L., Science and Technology Park of Gipuzkoa, San Sebastian, Spain.
School of Medicine, Istanbul Kemerburgaz University, Istanbul, Turkey.
SOMAprobes S.L., Science and Technology Park of Gipuzkoa, San Sebastian, Spain.
2016 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 52, no 83, 12346-12349 p.Article in journal (Refereed) Published
Abstract [en]

We report on the activity of nucleases derived from cancer cells as a means for specific targeting using nucleic acid probes (substrates). We hypothesize that cancer cells can be differentiated from healthy cells based on their nuclease activity profile, and thus, any method based on this property represents a novel alternative for diagnostic and therapeutic intervention.

Place, publisher, year, edition, pages
2016. Vol. 52, no 83, 12346-12349 p.
National Category
Natural Sciences Basic Medicine
Identifiers
URN: urn:nbn:se:liu:diva-142935DOI: 10.1039/c6cc07108bPubMedID: 27722495OAI: oai:DiVA.org:liu-142935DiVA: diva2:1156440
Available from: 2017-11-13 Created: 2017-11-13 Last updated: 2017-12-04

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