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Aptamers overview: selection, features and applications.
Biodonostia Research Institute, San Sebastian, Spain.
POLYMAT, University of the Basque Country UPV/EHU, San Sebastian, Spain.
POLYMAT, University of the Basque Country UPV/EHU, San Sebastian, Spain.
Biodonostia Research Institute, San Sebastian, Spain; POLYMAT, University of the Basque Country UPV/EHU, San Sebastian, Spain.
2015 (English)In: Current Topics in Medicinal Chemistry, ISSN 1568-0266, E-ISSN 1873-4294, Vol. 15, no 12, 1066-1081 p.Article in journal (Refereed) Published
Abstract [en]

Apatamer technology has been around for a quarter of a century and the field had matured enough to start seeing real applications, especially in the medical field. Since their discovery, aptamers rapidly emerged as key players in many fields, such as diagnostics, drug discovery, food science, drug delivery and therapeutics. Because of their synthetic nature, aptamers are evolving at an exponential rate gaining from the newest advances in chemistry, nanotechnology, biology and medicine. This review is meant to give an overview of the aptamer field, by including general aspects of aptamer identification and applications as well as highlighting certain features that contribute to their quick deployment in the biomedical field.

Place, publisher, year, edition, pages
Bentham science publishers , 2015. Vol. 15, no 12, 1066-1081 p.
National Category
Medical Biotechnology
Identifiers
URN: urn:nbn:se:liu:diva-142940DOI: 10.2174/1568026615666150413153717PubMedID: 25866270OAI: oai:DiVA.org:liu-142940DiVA: diva2:1156452
Note

Funding agencies:This work was supported by Biodonostia Research Institute (LIH and FJH). TS would like to acknowledge funding from the Spanish Ministry (CTQ2013-41113-R) and the Deputación Foral del Guipúzcoa (DG2014/08). FJH is supported by the Spanish Grant PIE13/00048, Proyectos integrados de excelencia de los Institutos de Investigación Sanitaria, Entidad financiadora: Ministerio de Economía y Competitividad (Instituto de Salud Carlos III).

Available from: 2017-11-13 Created: 2017-11-13 Last updated: 2017-12-04

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CiteExportLink to record
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