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Self-assessed remission rates after electroconvulsive therapy of depressive disorders
Örebro University, Sweden.
Örebro University, Sweden; Karolinska Institute, Sweden.
Umeå University Hospital, Sweden.
Lund University, Sweden.
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2017 (English)In: European psychiatry, ISSN 0924-9338, E-ISSN 1778-3585, Vol. 45, 154-160 p.Article in journal (Refereed) Published
Abstract [en]

Background: Electroconvulsive therapy (ECT) effectively treats severe depression, but not all patients remit. The aim of the study was to identify clinical factors that associate with ECT-induced remission in a community setting. Methods: Depressed patients who underwent ECT in 2011-2014 were identified from the Swedish National Quality Register for ECT. Remission was defined as self-rated Montgomery-Asberg Depression Rating Scale scores of 0-10 after ECT. Other registers provided data on previous antidepressant use, comorbidities, and demographics. Results: Of 1671 patients fulfilling the inclusion criteria, 42.8% achieved remission. Older age, education length over 9 years, psychotic symptoms, shorter duration of preceding antidepressant use, pulse width stimulus amp;gt;= 0.50 ms, absence of substance use disorders, anxiety diagnosis, lamotrigine, and benzodiazepines, were associated with remission. Conclusions: This study shows that psychotic subtype of depression and older age are clinically relevant predictors of a beneficial ECT effect. Additionally, ECT outcomes can be further improved by optimizing the treatment technique and concomitant medication. (C) 2017 The Author(s). Published by Elsevier Masson SAS.

Place, publisher, year, edition, pages
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER , 2017. Vol. 45, 154-160 p.
Keyword [en]
Mania and bipolar disorder; Unipolar depression; ECT
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:liu:diva-143103DOI: 10.1016/j.eurpsy.2017.06.015ISI: 000414461300021PubMedID: 28865389OAI: oai:DiVA.org:liu-143103DiVA: diva2:1159390
Note

Funding Agencies|Region Orebro county; Swedish research council [523-2013-2982]; Swedish foundation for strategic research [KF10-0039]

Available from: 2017-11-22 Created: 2017-11-22 Last updated: 2017-11-22

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Center for Social and Affective Neuroscience (CSAN)Faculty of Medicine and Health SciencesDepartment of Psychiatry
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CiteExportLink to record
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Citation style
  • apa
  • harvard1
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  • modern-language-association-8th-edition
  • vancouver
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  • Other style
More styles
Language
  • de-DE
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  • nn-NB
  • sv-SE
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Output format
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