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Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAG laser treatments with two aspheric hydrophobic acrylic intraocular lenses - a long-term intra-individual study
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Ophthalmology in Linköping. Linköping University, Faculty of Medicine and Health Sciences.
2017 (English)In: Acta Ophthalmologica, ISSN 1755-375X, E-ISSN 1755-3768, Vol. 95, no 7, 671-677 p.Article in journal (Refereed) Published
Abstract [en]

Purpose: To compare two hydrophobic acrylic intraocular lenses (IOLs) regarding long-term anterior/posterior capsular opacification (ACO/PCO) development and need for neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment due to visually disturbing PCO, and to study development of glistenings in the IOL materials. Methods: In a prospective, randomized, intra-individual, comparative trial, 50 cataract patients received either an AcrySof IQ((R)) SN60WF (Alcon, Fort Worth, TX, USA) or a Tecnis((R)) ZCB00 (Abbott Medical Optics, Santa Ana, CA, USA) IOL in the first operated eye, and the second eye received the IOL type not implanted in the first eye. Anterior/posterior capsular opacification (ACO/PCO) and fibrosis were monitored with slit-lamp photography and semi-automated digital analysis 2 and 3years postoperatively. Glistenings were semi-quantitatively assessed in slit-lamp photographs. Nd:YAG laser treatment for visually disturbing PCO was monitored. Results: Visual outcomes were similar for the two IOLs. Anterior capsular fibrosis and/or opacification developed more often in SN60WF eyes. Mean PCO area percentage was larger in ZCB00 eyes 3years after surgery, but severity score did not differ with statistical significance between the two IOLs. Six ZCB00 eyes and 2 SN60WF eyes underwent Nd:YAG laser treatment during a mean of 4years 8months after surgery. This difference was not statistically significant. A high amount of glistenings developed in most SN60WF IOLs, while only few ZCB00 IOLs displayed a low degree of glistenings. Conclusion: Visual outcomes, PCO development over time and need for Nd:YAG laser treatment were similar for the two IOLs. Anterior capsule fibrosis/contraction and glistenings were more pronounced with the SN60WF IOL.

Place, publisher, year, edition, pages
WILEY , 2017. Vol. 95, no 7, 671-677 p.
Keyword [en]
glistenings; hydrophobic acrylic; intraocular lens; posterior capsular opacification
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:liu:diva-143247DOI: 10.1111/aos.13444ISI: 000414648500028PubMedID: 28371401OAI: oai:DiVA.org:liu-143247DiVA: diva2:1160427
Note

Funding Agencies|Region of Ostergotland (ALF); Abbott Medical Optics; Alcon; Bausch + Lomb; Thea Laboratories; Zeiss

Available from: 2017-11-27 Created: 2017-11-27 Last updated: 2017-11-27

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Johansson, Björn
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Division of Neuro and Inflammation ScienceDepartment of Ophthalmology in LinköpingFaculty of Medicine and Health Sciences
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