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Staphylococcus epidermidis isolates from nares and prosthetic joint infections are mupirocin susceptible.
Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Faculty of Medicine and Health, Örebro University, Örebro, Sweden, Karlstad Hospital, Sweden.
Örebro University, Örebro, Sweden, Centre for Clinical Research, Hospital of Västmanland, Västerås, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Heart and Medicine Center, Department of Infectious Diseases.
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2018 (English)In: Journal of bone and joint infection, ISSN 2206-3552, Vol. 3, no 1, p. 1-4Article in journal (Refereed) Published
Abstract [en]

The objective of the present study was to investigate the antibiotic susceptibility including mupirocin among Staphylococcus. epidermidis isolated from prosthetic joint infections (PJIs) (n=183) and nasal isolates (n=75) from patients intended to undergo prosthetic joint replacements. Susceptibility to mupirocin (used for eradication of nasal carriership of Staphylococcus aureus) was investigated by gradient test, and susceptibility to various other antimicrobial agents was investigated by disc diffusion test. All isolates, except three from PJIs and one from the nares, were fully susceptible to mupirocin. Multi-drug resistance (≥3 antibiotic classes) was found in 154/183 (84.2%) of the PJI isolates but only in 2/75 (2.7%) of the nares isolates, indicating that S. epidermidis causing PJIs do not originate from the nares.

Place, publisher, year, edition, pages
2018. Vol. 3, no 1, p. 1-4
Keywords [en]
Antibiotic susceptibility testing, Mupirocin, Prosthetic joint infections, Staphylococcus epidermidis
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:liu:diva-144369DOI: 10.7150/jbji.22459PubMedID: 29291157OAI: oai:DiVA.org:liu-144369DiVA, id: diva2:1174910
Available from: 2018-01-17 Created: 2018-01-17 Last updated: 2018-01-25

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Nilsdotter-Augustinsson, Åsa
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CiteExportLink to record
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Citation style
  • apa
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