liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Oxidant-induced autophagy and ferritin degradation contribute to epithelial-mesenchymal transition through lysosomal iron
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Respiratory Medicine.
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Medicine and Health Sciences.
Division of Medicine, Ryhov Hospital, Jönköping, Sweden.
Division of Medicine, Hospital of Eksjö, Eksjö, Sweden.
Show others and affiliations
2017 (English)In: Journal of Inflammation Research, ISSN 1178-7031, E-ISSN 1178-7031, Vol. 10, p. 29-39Article in journal (Refereed) Published
Abstract [en]

Transforming growth factor (TGF)-ß1 triggers epithelial-mesenchymal transition (EMT) through autophagy, which is partly driven by reactive oxygen species (ROS). The aim of this study was to determine whether leaking lysosomes and enhanced degradation of H-ferritin could be involved in EMT and whether it could be possible to prevent EMT by iron chelation targeting of the lysosome.

Place, publisher, year, edition, pages
Dove Medical Press , 2017. Vol. 10, p. 29-39
Keyword [en]
A549 cells; COPD; pulmonary disease; pulmonary fibrosis; transforming growth factor; tumor necrosis factor
National Category
Immunology
Identifiers
URN: urn:nbn:se:liu:diva-145062DOI: 10.2147/JIR.S128292PubMedID: 28405169OAI: oai:DiVA.org:liu-145062DiVA: diva2:1181327
Available from: 2018-02-08 Created: 2018-02-08 Last updated: 2018-02-08

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Sioutas, ApostolosVainikka, LindaJacobson, PetraPersson, Hans Lennart
By organisation
Division of Cardiovascular MedicineFaculty of Medicine and Health SciencesDepartment of Respiratory MedicineDivision of Cell BiologyDepartment of Medical and Health Sciences
In the same journal
Journal of Inflammation Research
Immunology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 47 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf