liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Preoperative fluid retention increases blood loss during major open abdominal surgery
Research Unit, Södertälje Hospital, Södertälje, Sweden.
Linköping University, Department of Medical and Health Sciences, Division of Drug Research. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Anaesthesiology and Intensive Care in Linköping.
Linköping University, Department of Medical and Health Sciences, Division of Drug Research. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Anaesthesiology and Intensive Care in Linköping.
2017 (English)In: Perioperative Medicine, ISSN 0908-6919, E-ISSN 2047-0525, Vol. 6, no 12Article in journal (Refereed) Published
Abstract [en]

Background

Quantification of renal fluid conservation is possible by urine analysis, and the results can indicate dehydration. The present report sought to determine whether this fluid retention correlates with fluid requirements during major abdominal surgeries that have estimated operating times ≥ 2 h.

Methods

Urine colour, specific weight, osmolality and creatinine concentration were used to calculate a composite “fluid retention index” (FRI) in 97 patients prior to major abdominal surgery. Goal-directed fluid volume optimization, with hydroxyethyl starch supplemented with a background administration of crystalloid fluid, was used.

Results

The median preoperative FRI was 3.0. Fluid retention, considered as present when FRI ≥ 3.5, was found in 37% of the patients. Fluid retention was followed by a significantly larger blood loss (+ 125%; 450 vs. 200 ml), higher haemorrhage rate (+ 41%; 123 vs. 87 ml/h) and greater need for both colloid (+ 43%; 1.43 vs. 1.00 l) and crystalloid (+ 18%; 1.28 vs. 1.08 l) fluids. Despite the larger blood loss, the total fluid balance was more positive after surgery in the dehydrated patients (+ 26%; 1.91 vs. 1.51 l; P < 0.02).

Conclusions

Preoperative fluid retention, as detected in a urine sample, was associated with a greater blood loss and a more positive fluid balance during major abdominal surgery.

Place, publisher, year, edition, pages
BioMed Central, 2017. Vol. 6, no 12
Keywords [en]
Abdominal; Blood loss; Dehydration; Surgery; Urine specimen collection
National Category
Anesthesiology and Intensive Care
Identifiers
URN: urn:nbn:se:liu:diva-145041DOI: 10.1186/s13741-017-0068-1PubMedID: 28878889OAI: oai:DiVA.org:liu-145041DiVA, id: diva2:1181333
Available from: 2018-02-08 Created: 2018-02-08 Last updated: 2018-05-04Bibliographically approved

Open Access in DiVA

fulltext(735 kB)3 downloads
File information
File name FULLTEXT01.pdfFile size 735 kBChecksum SHA-512
2a76174356e5e91f31d98a6e99590678e69d24852d077135406c358097ed4fb7166739ab8b112b23552b0112b637ef971d16a54d04bdeea15d663f71a8b58bea
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Nilsson, Lena

Search in DiVA

By author/editor
Bahlmann, HansNilsson, Lena
By organisation
Division of Drug ResearchFaculty of Medicine and Health SciencesDepartment of Anaesthesiology and Intensive Care in Linköping
In the same journal
Perioperative Medicine
Anesthesiology and Intensive Care

Search outside of DiVA

GoogleGoogle Scholar
Total: 3 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 84 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf