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Experience of using MOSFET detectors for dose verification measurements in an end-to-end Ir-192 brachytherapy quality assurance system
Karolinska Univ Hosp, Sweden.
Karolinska Univ Hosp, Sweden.
Linköping University, Department of Medical and Health Sciences, Division of Radiological Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Radiation Physics. Linköping University, Center for Medical Image Science and Visualization (CMIV). Karolinska Univ Hosp, Sweden.
2018 (English)In: Brachytherapy, ISSN 1538-4721, E-ISSN 1873-1449, Vol. 17, no 1, p. 227-233Article in journal (Refereed) Published
Abstract [en]

PURPOSE: Establishment of an end-to-end system for the brachytherapy (BT) dosimetric chain could be valuable in clinical quality assurance. Here, the development of such a system using MOSFET (metal oxide semiconductor field effect transistor) detectors and experience gained during 2 years of use are reported with focus on the performance of the MOSFET detectors. METHODS AND MATERIALS: A bolus phantom was constructed with two implants, mimicking prostate and head amp; neck treatments, using steel needles and plastic catheters to guide the Ir-192 source and house the MOSFET detectors. The phantom was taken through the BT treatment chain from image acquisition to dose evaluation. During the 2-year evaluation-period, delivered doses were verified a total of 56 times using MOSFET detectors which had been calibrated in an external Co-60 beam. An initial experimental investigation on beam quality differences between Ir-192 and Co-60 is reported. RESULTS: The standard deviation in repeated MOSFET measurements was below 3% in the six measurement points with dose levels above 2 Gy. MOSFET measurements overestimated treatment planning system doses by 2-7%. Distance-dependent experimental beam quality correction factors derived in a phantom of similar size as that used for end-to-end tests applied on a time-resolved measurement improved the agreement. CONCLUSIONS: MOSFET detectors provide values stable over time and function well for use as detectors for end-to-end quality assurance purposes in 192Ir BT. Beam quality correction factors should address not only distance from source but also phantom dimensions. (C) 2017 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Place, publisher, year, edition, pages
ELSEVIER SCIENCE INC , 2018. Vol. 17, no 1, p. 227-233
Keywords [en]
Brachytherapy; Quality assurance; End-to-end; 192Ir; MOSFET
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:liu:diva-145479DOI: 10.1016/j.brachy.2017.09.005ISI: 000424964700027PubMedID: 29110967OAI: oai:DiVA.org:liu-145479DiVA, id: diva2:1187701
Note

Funding Agencies|Swedish Cancer Society (CF) [CAN 2015/618]; internal RDE fund at the Medical Radiation Physics and Nuclear Medicine at Karolinska University Hospital

Available from: 2018-03-05 Created: 2018-03-05 Last updated: 2018-03-05

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Carlsson Tedgren, Åsa
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Division of Radiological SciencesFaculty of Medicine and Health SciencesDepartment of Radiation PhysicsCenter for Medical Image Science and Visualization (CMIV)
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