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Distinct Neural-Functional Effects of Treatments With Selective Serotonin Reuptake Inhibitors, Electroconvulsive Therapy, and Transcranial Magnetic Stimulation and Their Relations to Regional Brain Function in Major Depression: A Meta-analysis
Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.
University of Tennessee, Knoxville, Tennessee, USA.
Linköping University, Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in Central Östergötland, Department of Psychiatry.
Laureate Institute for Brain Research, Tulsa, Oklahoma, USA; Janssen Research and Development, Janssen Pharmaceuticals of Johnson and Johnson, Titusville, New Jersey, USA.
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2017 (English)In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, ISSN 2451-9030, Vol. 2, no 4, p. 318-326Article in journal (Refereed) Published
Abstract [en]

Functional neuroimaging studies have examined the neural substrates of treatments for major depressive disorder (MDD). Low sample size and methodological heterogeneity, however, undermine the generalizability of findings from individual studies. We conducted a meta-analysis to identify reliable neural changes resulting from different modes of treatment for MDD and compared them with each other and with reliable neural functional abnormalities observed in depressed versus control samples.

Place, publisher, year, edition, pages
Elsevier, 2017. Vol. 2, no 4, p. 318-326
Keywords [en]
Electroconvulsive therapy; Major depressive disorder; Meta-analysis; Positron emission tomography; Selective serotonin reuptake inhibitors; Transcranial magnetic stimulation
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:liu:diva-146140DOI: 10.1016/j.bpsc.2017.01.003PubMedID: 29560920OAI: oai:DiVA.org:liu-146140DiVA, id: diva2:1194167
Available from: 2018-03-29 Created: 2018-03-29 Last updated: 2018-04-17

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Nordanskog, PiaHamilton, Paul J.

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Center for Social and Affective NeuroscienceFaculty of Medicine and Health SciencesDepartment of Psychiatry
Psychiatry

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