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Osteogenic potency of magnetic fibrin nanoparticles—A novel perspective in bone tissue engineering
Bio-Products Laboratory, Central Leather Research Institute, Adyar, Chennai 600020, Tamil Nadu, India.
Bio-Products Laboratory, Central Leather Research Institute, Adyar, Chennai 600020, Tamil Nadu, India.
Bio-Products Laboratory, Central Leather Research Institute, Adyar, Chennai 600020, Tamil Nadu, India.
norganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500607, Andhra Pradesh, India.
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2015 (English)In: Materials letters (General ed.), ISSN 0167-577X, E-ISSN 1873-4979, Vol. 139, p. 108-111Article in journal (Refereed) Published
Abstract [en]

In the present study, goat blood has been used as the starting material for the preparation of novel magnetic fibrin nanoparticles (MAG–FNPs) in tissue engineering. The synthesised nanoparticles were characterized by X-ray diffractometer (XRD), transmittance electron microscope (TEM), scanning electron microscope (SEM), Fourier Transform Infrared spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX) and vibrating sample magnetometer (VSM) analysis. The osteogenic potential of MAG–FNPs was evaluated by performing cell viability assay and quantifying alkaline phosphatase (ALP) levels using Saos-2 cells. The results obtained suggested that MAG–FNPs could serve as promising biomaterial for bone tissue engineering.

Place, publisher, year, edition, pages
2015. Vol. 139, p. 108-111
Keywords [en]
Nanoparticles, Magnetic materials, Electron microscopy, Saos-2, Cell viability
National Category
Natural Sciences Chemical Sciences
Identifiers
URN: urn:nbn:se:liu:diva-146243DOI: 10.1016/j.matlet.2014.10.045OAI: oai:DiVA.org:liu-146243DiVA, id: diva2:1195093
Available from: 2018-04-04 Created: 2018-04-04 Last updated: 2018-04-23

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Periyathambi, Prabu
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