liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA.
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA.
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA / Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA / Department of Child and Adolescent Psychiatry, New York University School of Medicine, 577 First Avenue, New York, NY 10016, USA.
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA / Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA / Department of Child and Adolescent Psychiatry, New York University School of Medicine, 577 First Avenue, New York, NY 10016, USA.
2009 (English)In: Neural Plasticity, ISSN 2090-5904, E-ISSN 1687-5443, Vol. 2009, article id 754014Article in journal (Refereed) Published
Abstract [en]

Dishabituation is a return of a habituated response if context or contingency changes. In the mammalian olfactory system, metabotropic glutamate receptor mediated synaptic depression of cortical afferents underlies short-term habituation to odors. It was hypothesized that a known antagonistic interaction between these receptors and norepinephrine -receptors provides a mechanism for dishabituation. The results demonstrate that a 108 dB siren induces a two-fold increase in norepinephrine content in the piriform cortex. The same auditory stimulus induces dishabituation of odor-evoked heart rate orienting bradycardia responses in awake rats. Finally, blockade of piriform cortical norepinephrine -receptors with bilateral intracortical infusions of propranolol (100  M) disrupts auditory-induced dishabituation of odor-evoked bradycardia responses. These results provide a cortical mechanism for a return of habituated sensory responses following a cross-modal alerting stimulus.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2009. Vol. 2009, article id 754014
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:liu:diva-150387DOI: 10.1155/2009/754014ISI: 000267027400001PubMedID: 19343110Scopus ID: 2-s2.0-65349144836OAI: oai:DiVA.org:liu-150387DiVA, id: diva2:1240556
Available from: 2018-08-21 Created: 2018-08-21 Last updated: 2018-08-29Bibliographically approved

Open Access in DiVA

Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation(1562 kB)54 downloads
File information
File name FULLTEXT01.pdfFile size 1562 kBChecksum SHA-512
83e7ccbbb72e07e141b6b06f033eb0a1d0185bbf29538419fba7ebab736be94ae6b96c37e64ed792f36226b842cffddad0090bb62d064eda39fdf2105a6f8a3d
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records BETA

Shionoya, Kiseko

Search in DiVA

By author/editor
Shionoya, Kiseko
In the same journal
Neural Plasticity
Neurosciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 54 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 66 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf