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Study protocol for an observational register-based study on health and risk factors in patients with hip and knee osteoarthritis
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences. Department of Physiotherapy, Rehabilitation Centre, Ryhov County Hospital Jönköping, Jönköping, Sweden.ORCID iD: 0000-0003-3403-229X
Department of Orthopaedics, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.
Linköping University, Department of Medical and Health Sciences. Linköping University, Faculty of Medicine and Health Sciences. Futurum, Region Jönköping County, Jönköping, Sweden.
Department of Clinical Sciences Lund, Orthopedics, Faculty of Medicine, Lund University and Clinical Epidemiology Unit, Skåne University Hospital, Lund, Sweden.
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2018 (English)In: BMJ Open, ISSN 2044-6055, E-ISSN 2044-6055, Vol. 8, no 10, article id e022812Article in journal (Refereed) Published
Abstract [en]

Introduction Hip and knee osteoarthritis is a leading cause of disability worldwide. Currently, the course of deterioration in pain and physical functioning in individuals with osteoarthritis is difficult to predict. Factors such as socioeconomic status and comorbidity contribute to progression of osteoarthritis, but clear associations have not been established. There is a need for early identification of individuals with slow disease development and a good prognosis, and those that should be recommended for future joint replacement surgery.

Methods and analysis This nationwide register-based study will use data for approximately 75 000 patients who sought and received core treatment for osteoarthritis in primary healthcare, and were registered in the Swedish population-based National Quality Register for Better Management of Patients with Osteoarthritis. These data will be merged with data for replacement surgery, socioeconomic factors, healthcare consumption and comorbidity from the Swedish Hip Arthroplasty Register, the Swedish Knee Arthroplasty Register, Statistics Sweden and the National Board of Health and Welfare, Sweden. The linkage will be performed using personal identity numbers that are unique to all citizens in Sweden.

Ethics and dissemination The study was approved by the Regional Ethical Review Board in Gothenburg, Sweden (dnr 1059–16). The results from this study will be submitted to peer-reviewed journals and reported at suitable national and international meetings.

Trial registration number NCT03438630.

Place, publisher, year, edition, pages
British Medical Journal Publishing Group , 2018. Vol. 8, no 10, article id e022812
National Category
Occupational Therapy
Identifiers
URN: urn:nbn:se:liu:diva-151890DOI: 10.1136/bmjopen-2018-022812ISI: 000454739500118OAI: oai:DiVA.org:liu-151890DiVA, id: diva2:1254309
Note

Funding agencies: AFA Insurance, Sweden [160176]; Futurum-Academy for Health and Care, Region Jonkoping County, Sweden [559951, 557821]

Available from: 2018-10-09 Created: 2018-10-09 Last updated: 2019-05-03

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Study protocol for an observational register-based study on health and risk factors in patients with hip and knee osteoarthritis(463 kB)72 downloads
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Gustafsson, KristinKvist, Joanna

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