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Three Years Experience of a Novel Biosynthetic Cellulose Dressing in Burns
Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery. Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery.
Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery.
Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Anaesthesiology and Intensive Care in Linköping.
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2018 (English)In: ADVANCES IN WOUND CARE, ISSN 2162-1918Article in journal (Refereed) Published
Abstract [en]

Objective: The use of porcine xenograft (PX) is widely spread in burn care. However, it may cause immunologic responses and other ethical and cultural considerations in different cultures. Therefore, there is a need for alternatives. The aim of this work is to test a novel biosynthetic cellulose dressing (Epiprotect((R))) on burn patients. Approach: Charts from 38 patients with superficial burns (SBs) (n=18) or excised burns (n=20) that got biosynthetic cellulose dressing instead of PX at a national burn center during 3 years were reviewed. Time to healing, length of stay, and wound infection were extracted from the medical records. Results: SBs hospitalization time was 11 days comparable to PXs reported by others. In the excised group, median duration of hospital stay was 35 days. Time to healing was 28 days. Seven wound infections were confirmed in the superficial group (39%) and 11 infections in the excised group (61%). Patients with superficial wounds reported pain relief on application. Innovation: A dressing (17x21cm) consisting of biosynthetic cellulose replacing PX. Conclusion: Outcome of treatment of SBs or temporary coverage of excised deep burns with biosynthetic cellulose is comparable to treatment with PX. However, biosynthetic cellulose has benefits such as providing pain relief on application and ethical or cultural issues with the material is nonexistent.

Place, publisher, year, edition, pages
MARY ANN LIEBERT, INC , 2018.
Keywords [en]
burns; cellulose; wound healing; dressing
National Category
Surgery
Identifiers
URN: urn:nbn:se:liu:diva-151940DOI: 10.1089/wound.2018.0790ISI: 000445706300001OAI: oai:DiVA.org:liu-151940DiVA, id: diva2:1256359
Note

Funding Agencies|National Burn Unit, the Department of Plastic Surgery, Hand Surgery, and Burns, Linkoping University Hospital in Sweden; Faculty of Health Sciences, Linkoping University in Sweden

Available from: 2018-10-16 Created: 2018-10-16 Last updated: 2019-05-01

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Karlsson, MatildaOlofsson, PiaSteinvall, IngridSjöberg, FolkeThorfinn, JohanElmasry, Moustafa
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Department of Hand and Plastic SurgeryDivision of Surgery, Orthopedics and OncologyFaculty of Medicine and Health SciencesDepartment of Anaesthesiology and Intensive Care in Linköping
Surgery

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