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Visual field defect during low-dose methotrexate therapy
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Ophthalmology in Linköping.
1992 (English)In: Documenta Ophthalmologica, ISSN 0012-4486, E-ISSN 1573-2622, Vol. 79, p. 91-94Article in journal (Refereed) Published
Abstract [en]

A patient was treated with low-dose methotrexate because of psoriasis that did not respond to conventional therapy. During treatment, visual symptoms occurred; optic disc swelling was found, and later slight optic disc atrophy. Moreover, paracentral relative visual field defects showed fluctuations parallel to methotrexate dose changes. It seems likely that methotrexate affected optic nerve function.

Place, publisher, year, edition, pages
Kluwer Academic Publishers, 1992. Vol. 79, p. 91-94
Keywords [en]
Methotrexate, toxicity, visual field defects, optic nerve affection
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:liu:diva-153465DOI: 10.1007/BF00160135PubMedID: 1568425OAI: oai:DiVA.org:liu-153465DiVA, id: diva2:1272269
Available from: 2018-12-18 Created: 2018-12-18 Last updated: 2019-03-22Bibliographically approved

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Johansson, Björn

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Division of Neuro and Inflammation ScienceFaculty of Medicine and Health SciencesDepartment of Ophthalmology in Linköping
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