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Prognostic Factors for Physical Functioning After Multidisciplinary Rehabilitation in Patients With Chronic Musculoskeletal Pain A Systematic Review and Meta-Analysis
Karolinska Inst, Sweden.
Orebro Univ, Sweden.
Karolinska Inst, Sweden; Danderyd Hospital, Sweden; Umea Univ, Sweden.
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in West Östergötland, Research & Development Unit in Local Health Care.ORCID iD: 0000-0003-3707-5869
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2019 (English)In: The Clinical Journal of Pain, ISSN 0749-8047, E-ISSN 1536-5409, Vol. 35, no 2, p. 148-173Article, review/survey (Refereed) Published
Abstract [en]

Objectives: This systematic review aimed to identify and evaluate prognostic factors for long-term (amp;gt;= 6 mo) physical functioning in patients with chronic musculoskeletal pain following multidisciplinary rehabilitation (MDR). Materials and Methods: Electronic searches conducted in MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, and Cochrane CENTRAL revealed 25 original research reports, published 1983-2016, (n=9436). Potential prognostic factors relating to initial pain and physical and psychological functioning were synthesized qualitatively and quantitatively in random effects meta-analyses. The level of evidence (LoE) was evaluated with Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results: Pain-related factors (intensity and chronicity) were not associated with function/disability at long-term follow-up, odds ratio (OR)=0.84; 95% confidence interval (CI), 0.65-1.07 and OR=0.97; 95% CI, 0.93-1.00, respectively (moderate LoE). A better function at follow-up was predicted by Physical factors; higher levels of initial self-reported functioning, OR= 1.07; 95% CI, 1.02-1.13 (low LoE), and Psychological factors; low initial levels of emotional distress, OR= 0.77; 95% CI, 0.65-0.92, low levels of cognitive and behavioral risk factors, OR=0.85; 95% CI, 0.77-0.93 and high levels of protective cognitive and behavioral factors, OR=1.49; 95% CI, 1.17-1.90 (moderate LoE). Discussion: While pain intensity and long-term chronicity did not predict physical functioning in chronic pain patients after MDR, poor pretreatment physical and psychological functioning influenced the prognosis negatively. Thus, treatment should further target and optimize these modifiable factors and an increased focus on positive, psychological protective factors may perhaps provide an opening for yet untapped clinical gains.

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS , 2019. Vol. 35, no 2, p. 148-173
Keywords [en]
chronic musculoskeletal pain; GRADE; interdisciplinary rehabilitation; meta-analysis; prognostic factors; treatment outcome
National Category
Physiotherapy
Identifiers
URN: urn:nbn:se:liu:diva-154667DOI: 10.1097/AJP.0000000000000669ISI: 000458401700006PubMedID: 30371517OAI: oai:DiVA.org:liu-154667DiVA, id: diva2:1293199
Note

Funding Agencies|Swedish Research Council; Doctoral School in Health Care Sciences, Karolinska Institutet, Sweden; AFA-Insurance Sweden; Research-ALF; County Council of Ostergotland, Linkoping; Swedish Research Council for Health, Working Life and Welfare (FORTE)

Available from: 2019-03-04 Created: 2019-03-04 Last updated: 2019-03-04

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