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Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study
CIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; University of Naples Federico II, Naples, Italy.
UCIBIO, REQUIMTE, Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), University of Porto, Porto, Portugal.
UCIBIO, REQUIMTE, Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), University of Porto, Porto, Portugal.
Woolcock Institute of Medical Research, University of Sydney Woolcock Emphysema Centre and Sydney Local Health District, Glebe, NSW, Australia.
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2019 (English)In: Clinical and Experimental Allergy, ISSN 0954-7894, E-ISSN 1365-2222, Vol. 49, no 4, p. 442-460Article in journal (Refereed) Published
Abstract [en]

Background

Mobile technology may help to better understand the adherence to treatment. MASK‐rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient‐centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries.

Objectives

To assess the adherence to treatment in allergic rhinitis patients using the Allergy DiaryApp.

Methods

An observational cross‐sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach.

Results

A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty‐six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non‐adherent to medications (MPR <70%). Of those, the largest group was non‐adherent to medications and the time interval was increased in 442 (36.68%) users.

Conclusion and clinical relevance

Adherence to treatment is low. The relative efficacy of continuous vs on‐demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication‐taking behaviour in a real‐world setting.

Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Inc., 2019. Vol. 49, no 4, p. 442-460
Keywords [en]
adherence; mHealth; mobile technology; observational study; rhinitis; treatment
National Category
Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:liu:diva-158062DOI: 10.1111/cea.13333ISI: 000463761700007PubMedID: 30597673Scopus ID: 2-s2.0-85063011308OAI: oai:DiVA.org:liu-158062DiVA, id: diva2:1329113
Available from: 2019-06-24 Created: 2019-06-24 Last updated: 2021-02-04Bibliographically approved

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Benson, Mikael

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