liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A red- emissive mitochondrial probe for imaging of the viscosity in living cells
Wannan Med Coll, Peoples R China.
Wannan Med Coll, Peoples R China.
Wannan Med Coll, Peoples R China.
Wannan Med Coll, Peoples R China.
Show others and affiliations
2019 (English)In: New Journal of Chemistry, ISSN 1144-0546, E-ISSN 1369-9261, Vol. 43, no 22, p. 8811-8815Article in journal (Refereed) Published
Abstract [en]

A novel water- soluble fluorescent probe L based on indole salts has been designed, synthesized and fully characterized. The systematic investigations demonstrated that probe L shows red emission and the fluorescence intensity is linear with the viscosity of the medium. Probe L is able to selectively accumulate in mitochondria within 1 min without any additional reagents for membrane permeabilization. It has been used to distinguish the viscosity differences between mitochondria in normal and nystatin- treated HeLa cells. In addition, due to the good photostability, probe L can be used to monitor the dynamics of mitochondria. These results support that probe L might provide a promising approach for the fluorescence detection of mitochondrial viscosity in living biological systems.

Place, publisher, year, edition, pages
ROYAL SOC CHEMISTRY , 2019. Vol. 43, no 22, p. 8811-8815
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:liu:diva-158866DOI: 10.1039/c9nj01826cISI: 000470919700049OAI: oai:DiVA.org:liu-158866DiVA, id: diva2:1337593
Note

Funding Agencies|Anhui Provincial Natural Science Foundation [1908085QB50]; Doctoral Startup Foundation of Wannan Medical College [wYRCQD201715]; Young Foundation of Wannan Medical College [WK201807]; Natural Science Fund of Education Department of Anhui province [KJ2018A0257]; National Natural Science Foundation of China [21602157]; Swedish Government strategic faculty grant in material science (SFO, MATLIU) in Advanced Functional Materials (AFM) (VR) [5.1-2015-5959]; Scientific Research Foundation for Academic and Technical Leader Reserve Candidate of Anhui Province [2016H086]

Available from: 2019-07-16 Created: 2019-07-16 Last updated: 2019-07-16

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text

Search in DiVA

By author/editor
Uvdal, KajsaHu, Zhang-Jun
By organisation
Molecular Surface Physics and Nano ScienceFaculty of Science & Engineering
In the same journal
New Journal of Chemistry
Organic Chemistry

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 36 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf