liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Tobacco smoking and alcohol consumption as risk factors for thymoma - A European case-control study
Lund Univ, Sweden; Skane Univ Hosp, Sweden.
Univ Southern Denmark, Denmark; Odense Univ Hosp, Denmark.
Aalborg Hosp, Denmark.
Inst Portugues Oncol IPO Porto, Portugal.
Show others and affiliations
2019 (English)In: Cancer Epidemiology, ISSN 1877-7821, E-ISSN 1877-783X, Vol. 61, p. 133-138Article in journal (Refereed) Published
Abstract [en]

Purpose: Hardly anything is known about the aetiology of thymoma. This paper presents data regarding tobacco smoking and alcohol consumption in relation to thymoma from the first case-control study performed on this rare tumour. Methods: A European multi-centre case-control study including incident cases aged 35-69 years with thymoma between 1995 and 1997, was conducted in seven countries. A set of controls, used in seven parallel case-control studies by the same research group was used, including population-based controls from five countries and hospital controls with colon cancer from two countries. Altogether 103 cases, accepted by a reference pathologist, 712 colon cancer controls, and 2071 population controls were interviewed. Results: Tobacco smoking was moderately related with thymoma (OR 1.4, 95% CI 0.9-2.2), and a tendency to dose-response was shown (p = 0.04), with an increased risk for heavy smokers defined as amp;gt;= 41 pack-years (OR 2.1, 95% CI 1.1-3.9). A high consumption of spirits defined as amp;gt;= 25 g of alcohol per day was associated with an increased risk of thymoma (OR 2.4, 95% CI 1.1-5.4), whereas no association was found with beer or wine. Conclusions: Tobacco smoking and a high intake of spirits were indicated as risk factors for thymoma.

Place, publisher, year, edition, pages
ELSEVIER SCI LTD , 2019. Vol. 61, p. 133-138
Keywords [en]
Thymoma; Thymus cancer; Tobacco smoking; Alcohol; Risk factors; Case-control study
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:liu:diva-159565DOI: 10.1016/j.canep.2019.06.008ISI: 000476631100018PubMedID: 31254794OAI: oai:DiVA.org:liu-159565DiVA, id: diva2:1342465
Note

Funding Agencies|European Commission [BMH1 CT 93-1630]; Denmark: The strategic Environment Programme [92.01.015.7-06]; Denmark: Danish Epidemiology Science Centre - Danish National Research Foundation; France: Ligue Nationale contre le cancer; France: Federation Nationale des Centres de Lutte contre le Cancer; France: Fondation de France [955368]; France: Institut National de la Sante et de la Recherche Medicale (INSERM) [4R006A]; France: French Ministry of Environment [237.01.94.40182]; Germany: Federal Ministry for Education, Science, Research and Technology (BMBF) [01-HP-684/8]; Italy: The Italian Association for Cancer Research (AIRC), Special Project Oncology, Compagnia di San Paolo/FIRMS, MURST, Region Piedmont; Spain: Fondo de Investigacion de la Sanitarie; Spain: Departmento de Sanidad y Consumo, Gobierno Vasco; Spain: Fondo de Investigacion de la Sanitaria, Ministerio de Sanidad y Consumo, Ayuda a la Investigacion del Departamento de Salud del Gobierno de Navarra; Sweden: Swedish Council for Work Life Research; Sweden: Research Foundation of the Department of Oncology in Umea; Sweden: Swedish Society of Medicine; Sweden: Lund University Hospital Research Foundation; Sweden: Gunnar, Arvid and Elisabeth Nilsson Cancer Foundation; Sweden: Orebro County Council Research Committee; Sweden: Orebro Medical Center Research Foundation; Sweden: John and Augusta Persson Foundation for Scientific Medical Research; Sweden: Berta Kamprad Foundation for Cancer Research; Spain: Ministerio de Sanidad y Consumo; Spain: Unidad de Investigacion Clinico-Epidemiologica; Spain: Hospital Dr. Peset. Generalitat Valenciana [FISS. 95/0044-01, 96/0043-01]

Available from: 2019-08-13 Created: 2019-08-13 Last updated: 2019-08-13

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Wingren, Gun
By organisation
Division of Neuro and Inflammation ScienceFaculty of Medicine and Health Sciences
In the same journal
Cancer Epidemiology
Public Health, Global Health, Social Medicine and Epidemiology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf