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Need for technologies in advanced corneal research, diagnosis, and transplantation
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Ophthalmology in Linköping.ORCID iD: 0000-0003-1079-4361
2019 (English)In: OPHTHALMIC TECHNOLOGIES XXIX, SPIE-INT SOC OPTICAL ENGINEERING , 2019, Vol. 10858, article id 108580BConference paper, Published paper (Refereed)
Abstract [en]

Never before have optical, information, and biomedical technologies converged to the extent they do today. Moreover, the accessibility of enormous amounts of computing power at reasonable cost has transformed raw data into useable information that can enable biological discoveries and medical decisions to be made faster and more accurate than ever before. In the field of ophthalmology in particular, advanced optical instrumentation, devices, and procedures have revolutionized the standard of care and improved outcomes for millions, for the benefit of society. The cornea is the clear outer window of the eye and is directly accessible for examination and treatment using light-based approaches, and as such it provides us with a unique window into the physiology of the body in health and disease. At the same time, the cornea is a model tissue from which we have acquired much knowledge about light-tissue interactions. Finally, and importantly, diseases of the cornea compromising its transparency are responsible for millions of cases of corneal blindness globally, so there is much to gain from technological advancements in the field. Here, a need for new technological solutions is presented, that is not primarily technology-driven but instead motivated by real and pressing medical needs in the research, diagnosis and treatment of corneal blindness.

Place, publisher, year, edition, pages
SPIE-INT SOC OPTICAL ENGINEERING , 2019. Vol. 10858, article id 108580B
Series
Proceedings of SPIE, ISSN 0277-786X
Keywords [en]
corneal blindness; transplantation; ophthalmology; photodynamic therapy; confocal microscopy; keratitis; tear film; tissue engineering
National Category
Biomedical Laboratory Science/Technology
Identifiers
URN: urn:nbn:se:liu:diva-160069DOI: 10.1117/12.2520656ISI: 000481649100002ISBN: 978-1-5106-2359-0 (print)OAI: oai:DiVA.org:liu-160069DiVA, id: diva2:1348153
Conference
Conference on Ophthalmic Technologies XXIX
Available from: 2019-09-03 Created: 2019-09-03 Last updated: 2019-09-03

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Lagali, Neil
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Division of Neuro and Inflammation ScienceFaculty of Medicine and Health SciencesDepartment of Ophthalmology in Linköping
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CiteExportLink to record
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Citation style
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