liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Hybrid Rhodamine Fluorophores in the Visible/NIR Region for Biological Imaging
Nanjing Tech Univ, Peoples R China; Nanjing Tech Univ, Peoples R China.
Northwestern Polytech Univ, Peoples R China.
Linköping University, Department of Physics, Chemistry and Biology, Molecular Surface Physics and Nano Science. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0001-9905-0881
Linköping University, Department of Physics, Chemistry and Biology, Molecular Surface Physics and Nano Science. Linköping University, Faculty of Science & Engineering.
Show others and affiliations
2019 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 58, no 40, p. 14026-14043Article, review/survey (Refereed) Published
Abstract [en]

Fluorophores and probes are invaluable for the visualization of the location and dynamics of gene expression, protein expression, and molecular interactions in complex living systems. Rhodamine dyes are often used as scaffolds in biological labeling and turn-on fluorescence imaging. To date, their absorption and emission spectra have been expanded to cover the entire near-infrared region (650-950 nm), which provides a more suitable optical window for monitoring biomolecular production, trafficking, and localization in real time. This review summarizes the development of rhodamine fluorophores since their discovery and provides strategies for modulating their absorption and emission spectra to generate specific bathochromic-shifts. We also explain how larger Stokes shifts and dual-emissions can be obtained from hybrid rhodamine dyes. These hybrid fluorophores can be classified into various categories based on structural features including the alkylation of amidogens, the substitution of the O atom of xanthene, and hybridization with other fluorophores.

Place, publisher, year, edition, pages
WILEY-V C H VERLAG GMBH , 2019. Vol. 58, no 40, p. 14026-14043
Keywords [en]
bioimaging; fluorescent probes; hybrid fluorophores; near-infrared region; rhodamine
National Category
Biophysics
Identifiers
URN: urn:nbn:se:liu:diva-160985DOI: 10.1002/anie.201901061ISI: 000487853000002PubMedID: 30843646OAI: oai:DiVA.org:liu-160985DiVA, id: diva2:1370178
Note

Funding Agencies|National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81672508]

Available from: 2019-11-14 Created: 2019-11-14 Last updated: 2019-11-14

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Hu, Zhang-JunUvdal, Kajsa
By organisation
Molecular Surface Physics and Nano ScienceFaculty of Science & Engineering
In the same journal
Angewandte Chemie International Edition
Biophysics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 3 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf