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Förtidsbörd största perinatala problemet [Preterm delivery an overview on epidemiology, pathophysiology and consequences for the individual and the society]
Avdelningen för Obstetrik och Gynekologi Göteborg, Sweden.
Karolinska institutet, Sweden.
Göteborgs universitet, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus Linköping/Motala.
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2019 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 116, article id FR6FArticle, review/survey (Refereed) Published
Abstract [sv]

Preterm delivery in Sweden constitutes 5.7 % of all deliveries, which is among the lowest rates in the world. There has not been any increase in the proportion of iatrogenic preterm deliveries during the last decades.The main hypothesis concerning the causality of preterm delivery is still that of the ascending infection from the vagina to the uterus and inflammation resulting in contractions, rupture of membranes and delivery. The mechanisms behind parturition at term are still elusive and this is also true for preterm delivery. The genetic contribution to preterm delivery is about 25-30 %. The first genes that are associated with preterm delivery and gestational duration have recently been published. Huge progress has been made in care of preterm born infants. Sweden has among the lowest rates of mortality and morbidity in the world, especially in the lowest gestational weeks. New modes of care, family-centered care and hospital-assisted home care, have empowered the parents and reduced the cost for care.

Abstract [sv]

Förtidsbörd utgör 5,7 procent av alla förlossningar i Sverige. Internationellt rapporteras från vissa länder upp till 18 procent. 

Den biologiska förståelsen av de mekanismer som resulterar i förtidsbörd är fortfarande mycket begränsad. 

Neonatalvården av för tidigt födda barn har gjort mycket stora framsteg under de senaste decennierna. Nya vårdformer har etablerats, t ex familjecentrerad vård och sjukhusassisterad hemvård i slutet av vårdtiden.

Cirka 15 miljoner barn föds för tidigt i världen varje år. De flesta av dem är födda under graviditetsvecka 32–36 och svarar för huvuddelen av mortalitet och neurologiska funktionshinder bland för tidigt födda. 

Place, publisher, year, edition, pages
Läkartidningen Förlag AB , 2019. Vol. 116, article id FR6F
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:liu:diva-165417PubMedID: 31593284OAI: oai:DiVA.org:liu-165417DiVA, id: diva2:1427793
Available from: 2020-05-01 Created: 2020-05-01 Last updated: 2020-05-01Bibliographically approved

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Abrahamsson, Thomas

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Division of Children's and Women's healthFaculty of Medicine and Health SciencesH.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus Linköping/Motala
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