Remanufacturing is a crucial component for our societies tomove toward a circular economy. Compared to newmanufacturing, the distinctive nature of remanufacturing isfound to have high variability, high uncertainty and, thereby,complexity. Therefore, remanufacturers need to enhance theirability to adjust their systems flexibly. Especially, the ability toreconfigure the production planning and control is crucial forreacting to the high variability and uncertainty. However, fewpractical methods to do that are available so far. Therefore, tosolve this problem, this paper aims to propose a method fordesigning processes of production planning and control inremanufacturing based on the concept of loosely coupledsystems. In the proposed method, Design Structure Matrix(DSM) is applied to identify loosely coupled subsystems thatenable to localize impacts of changes within themselves. Thesesubsystems are also utilized to appropriately determine leveragepoints, as well as allocate human resource. Through theapplication to a real case of remanufacturing, the proposedmethod was found to be effective for reconfiguring teams andprocesses for production planning and control depending ongiven uncertainties, as well as performing production planningand control activities efficiently.