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Implantable cardiac devices in adult patients with repaired tetralogy of Fallot
Umea Univ, Sweden.
Umea Univ, Sweden.
Umea Univ, Sweden.
Lund Univ, Sweden.
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2021 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 55, no 1, p. 22-28Article in journal (Refereed) Published
Abstract [en]

Objectives Implantable cardiac devices are common in patients with tetralogy of Fallot (ToF) (18.3-21.3%) according to previous reports from large centres. We conducted this study to investigate the prevalence and incidence of cardiac devices in a less selected population of patients with ToF and assess factors other than arrhythmia associated with having a device.Design:530 adult (>= 18 years) patients with repaired ToF were identified in the national registry of congenital heart disease (SWEDCON) and matched with data from the Swedish pacemaker registry. Patients with implantable cardiac devices were compared with patients without devices.Results: Seventy-five patients (14.2%) had a device; 51 (9.6%) had a pacemaker and 24 (4.5%) had an implantable cardioverter defibrillator. The incidence in adult age (>= 18 years) was 5.9/1000 patient years. Estimated device free survival was 97.5% at twenty, 87.2% at forty and 63.5% at sixty years of age. Compared with previous studies, the prevalence of devices was lower, especially for ICD. In multivariate logistic regression, cardiovascular medication (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.8-6.8), impaired left ventricular function, (OR 2.6, 95%CI 1.3-5.0) and age (OR 1.02, 95%CI 1.002-1.05) were associated with having a device.Conclusion: The prevalence of devices in our population, representing a multicenter register cohort, was lower than previously reported, especially regarding ICD. This can be due to differences in treatment traditions with regard to ICD in this population, but it may also be that previous studies have reported selected patients with more severe disease.

Place, publisher, year, edition, pages
TAYLOR & FRANCIS LTD , 2021. Vol. 55, no 1, p. 22-28
Keywords [en]
Tetralogy of Fallot; pacemaker; implantable cardioverter defibrillator; congenital heart disease; register
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General Practice
Identifiers
URN: urn:nbn:se:liu:diva-168520DOI: 10.1080/14017431.2020.1792973ISI: 000548989400001PubMedID: 32672076OAI: oai:DiVA.org:liu-168520DiVA, id: diva2:1462210
Note

Funding Agencies|Swedish Heart-Lung FoundationSwedish Heart-Lung Foundation; Umea University; County of Vasterbotten; Heart Foundation of Northern Sweden; Visare Norr.

Available from: 2020-08-28 Created: 2020-08-28 Last updated: 2022-04-26

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Nielsen, Niels Erik
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Division of Cardiovascular MedicineFaculty of Medicine and Health SciencesDepartment of Cardiology in Linköping
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