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2D MoS2 -Based Nanomaterials for Therapeutic, Bioimaging, and Biosensing Applications
School of Basic Sciences, Indian Institute of Technology Mandi, Kamand, Mandi, 175005, Himachal Pradesh, India.
School of Basic Sciences, Indian Institute of Technology Mandi, Kamand, Mandi, 175005, Himachal Pradesh, India.
School of Basic Sciences, Indian Institute of Technology Mandi, Kamand, Mandi, 175005, Himachal Pradesh, India.
Linköping University, Department of Science and Technology, Laboratory of Organic Electronics. Linköping University, Faculty of Science & Engineering.
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2019 (English)In: Small, ISSN 1613-6810, E-ISSN 1613-6829, Vol. 15, no 1Article, review/survey (Refereed) Published
Abstract [en]

Molybdenum disulfide (MoS2 ), a typical layered 2D transition metal dichalcogenide, has received colossal interest in the past few years due to its unique structural, physicochemical, optical, and biological properties. While MoS2 is mostly applied in traditional industries such as dry lubricants, intercalation agents, and negative electrode material in lithium-ion batteries, its 2D and 0D forms have led to diverse applications in sensing, catalysis, therapy, and imaging. Herein, a systematic overview of the progress that is made in the field of MoS2 research with an emphasis on its different biomedical applications is presented. This article provides a general discussion on the basic structure and property of MoS2 and gives a detailed description of its different morphologies that are synthesized so far, namely, nanosheets, nanotubes, and quantum dots along with synthesis strategies. The biomedical applications of MoS2 -based nanocomposites are also described in detail and categorically, such as in varied therapeutic and diagnostic modalities like drug delivery, gene delivery, phototherapy, combined therapy, bioimaging, theranostics, and biosensing. Finally, a brief commentary on the current challenges and limitations being faced is provided, along with a discussion of some future perspectives for the overall improvement of MoS2 -based nanocomposites as a potential nanomedicine.

Place, publisher, year, edition, pages
2019. Vol. 15, no 1
Keywords [en]
2D material; molybdenum disulfide; sensing; theranostics; therapy
National Category
Materials Chemistry
Identifiers
URN: urn:nbn:se:liu:diva-168720DOI: 10.1002/smll.201803706ISI: 000454953900021PubMedID: 30565842OAI: oai:DiVA.org:liu-168720DiVA, id: diva2:1462355
Available from: 2020-08-28 Created: 2020-08-28 Last updated: 2024-10-28

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