liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Sputuminduktion bör väljas före ventrikelsköljning vid tbc-prov [Is it time to use sputum induction as a complementary specimen collection procedure in adult patients with suspected pulmonary tuberculosis?]
Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden.
Department of Infection Control and Hospital Hygiene, Stockholm County Council, Stockholm, Sweden.
Remeo, Stockholm.
Karolinska universitetslaboratoriet, Stockholm, Sweden.
Show others and affiliations
2020 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 117, article id 20039Article in journal (Refereed) Published
Abstract [en]

Gastric aspiration (GA) and sputum induction (SI) are used for diagnosing pulmonary tuberculosis (TB) in patients who cannot spontaneously produce sputum. This meta-analysis compares the sensitivity of GA and SI as alternative strategies for TB specimen collection in adult patients and describes procedure preference across Swedish Departments for Infectious Diseases (DID). We searched PubMed for articles on SI, GA and TB in adults. The meta-analysis included six articles (418 patients) and resulted in a crude OR 3.5 (95% CI 1.6-7.8) for positive culture from SI compared with GA. We asked all DID which procedure they currently used for collecting TB specimens (Sep 2019). Answers were received from 27/29 DID of which 67% (18/27) used SI as the primary diagnostic strategy when a patient could not spontaneously submit sputum. In conclusion, SI seems more effective than GA in detecting culture positive pulmonary TB in adult patients.

Abstract [sv]

Ventrikelsköljning och sputuminduktion är alternativadiagnostiska metoder för vuxna patienter med misstänkt lungtuberkulos som inte kan producera sputumeller med negativt resultat vid mikroskopi och PCR förmykobakterier i sputumprov.

Sputuminduktion är en känsligare metod än ventrikelsköljning för tuberkulosdiagnostik och är förenad medmindre obehag för patienten.

Både sputuminduktion och ventrikelsköljning börutföras i isoleringsrum avsett för luftburen smitta, ochpersonal ska använda andningsskydd med filterfunktionav typen FFP3.

Place, publisher, year, edition, pages
Stockholm, Sweden: Läkartidningen Förlag AB , 2020. Vol. 117, article id 20039
National Category
Clinical Laboratory Medicine
Identifiers
URN: urn:nbn:se:liu:diva-173447PubMedID: 32940905OAI: oai:DiVA.org:liu-173447DiVA, id: diva2:1529821
Available from: 2021-02-19 Created: 2021-02-19 Last updated: 2021-03-20Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

PubMedArticle full text

Search in DiVA

By author/editor
Schön, Thomas
By organisation
Division of Inflammation and InfectionFaculty of Medicine and Health Sciences
In the same journal
Läkartidningen
Clinical Laboratory Medicine

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 61 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf