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The global case fatality rate of coronavirus disease 2019 by continents and national income: A meta-analysis
Case Western Reserve Univ, OH 44106 USA.
Yonsei Univ, South Korea.
Inje Univ, South Korea.
Yonsei Univ, South Korea.
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2022 (English)In: Journal of Medical Virology, ISSN 0146-6615, E-ISSN 1096-9071, Vol. 94, no 6, p. 2402-2413Article in journal (Refereed) Published
Abstract [en]

The aim of this study is to provide a more accurate representation of COVID-19s case fatality rate (CFR) by performing meta-analyses by continents and income, and by comparing the result with pooled estimates. We used multiple worldwide data sources on COVID-19 for every country reporting COVID-19 cases. On the basis of data, we performed random and fixed meta-analyses for CFR of COVID-19 by continents and income according to each individual calendar date. CFR was estimated based on the different geographical regions and levels of income using three models: pooled estimates, fixed- and random-model. In Asia, all three types of CFR initially remained approximately between 2.0% and 3.0%. In the case of pooled estimates and the fixed model results, CFR increased to 4.0%, by then gradually decreasing, while in the case of random-model, CFR remained under 2.0%. Similarly, in Europe, initially, the two types of CFR peaked at 9.0% and 10.0%, respectively. The random-model results showed an increase near 5.0%. In high-income countries, pooled estimates and fixed-model showed gradually increasing trends with a final pooled estimates and random-model reached about 8.0% and 4.0%, respectively. In middle-income, the pooled estimates and fixed-model have gradually increased reaching up to 4.5%. in low-income countries, CFRs remained similar between 1.5% and 3.0%. Our study emphasizes that COVID-19 CFR is not a fixed or static value. Rather, it is a dynamic estimate that changes with time, population, socioeconomic factors, and the mitigatory efforts of individual countries.

Place, publisher, year, edition, pages
WILEY , 2022. Vol. 94, no 6, p. 2402-2413
Keywords [en]
case fatality rate; continents; COVID-19; proportion meta-analysis
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:liu:diva-183772DOI: 10.1002/jmv.27610ISI: 000760912100001PubMedID: 35099819OAI: oai:DiVA.org:liu-183772DiVA, id: diva2:1646995
Available from: 2022-03-24 Created: 2022-03-24 Last updated: 2023-02-28Bibliographically approved

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Dragioti, Elena

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Division of Prevention, Rehabilitation and Community MedicineFaculty of Medicine and Health SciencesPain and Rehabilitation Center
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