Soft lithographic printing of patterns of stretched DNA and DNA/electronic polymer wires by surface-energy modification and transfer
2006 (English)In: Small, ISSN 1613-6810 (print), 1613-6829 (online), Vol. 2, no 8-9, 1068-1074 p.Article in journal (Refereed) Published
Aligned and stretched λ DNA is directed to specific locations on solid substrates. Surface-energy modification of glass substrates by using patterned polydimethylsiloxane (PDMS) stamps is used to direct DNA onto the surface-energy-modified micrometer-scale pattern through molecular combing. As an alternative, patterned and nonpatterned PDMS stamps modified with polymethylmethacrylate (PMMA) are utilized to direct the stretched DNA to the desired location and the results are compared. The DNA is elongated through molecular combing on the stamp and transfer printed onto the surfaces. PMMA-modified stamps show a more defined length of the stretched DNA, as compared to bare PDMS stamps. A combination of these two methods is also demonstrated. As an application example, transfer printing of DNA decorated with a semiconducting conjugated polyelectrolyte is shown. The resulting patterned localization of stretched DNA can be utilized for functional nanodevice structures, as well as for biological applications.
Place, publisher, year, edition, pages
2006. Vol. 2, no 8-9, 1068-1074 p.
conjugation, DNA, lithography, patterning, polymers
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-12728DOI: 10.1002/smll.200600126OAI: oai:DiVA.org:liu-12728DiVA: diva2:16930