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Determination of autoantibodies in type 2 diabetes: one simple way to improve classification
Linköping University, Department of Biomedical and Clinical Sciences, Division of Children's and Women's Health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus.ORCID iD: 0000-0003-1695-5234
2023 (English)In: Diabetologia, ISSN 0012-186X, E-ISSN 1432-0428, Vol. 66, p. 955-957Article in journal, Letter (Other academic) Published
Abstract [en]

This letter aims to increase interest in better classification of type 2 diabetes. This can be done in a simple and cheap way via determination of autoantibodies. Autoantibody analysis can be used to detect the 7-12% of people with diabetes that is phenotypic of type 2 diabetes but is, in fact, latent autoimmune diabetes in adults (LADA), which may be regarded as a variant of type 1 diabetes. This may help to explain why some individuals with type 2 diabetes do not go into remission after reducing their weight, while others do, and why remission sometimes ends earlier than expected. Improved classification of diabetes may play an important role in determining adequate therapy.

Place, publisher, year, edition, pages
SPRINGER , 2023. Vol. 66, p. 955-957
Keywords [en]
GAD autoantibodies; LADA; Remission; Type 1 diabetes; Type 2 diabetes
National Category
Endocrinology and Diabetes
Identifiers
URN: urn:nbn:se:liu:diva-191633DOI: 10.1007/s00125-022-05858-4ISI: 000912296900002PubMedID: 36629876OAI: oai:DiVA.org:liu-191633DiVA, id: diva2:1734481
Available from: 2023-02-06 Created: 2023-02-06 Last updated: 2024-03-22

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Ludvigsson, Johnny
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Division of Children's and Women's HealthFaculty of Medicine and Health SciencesH.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus
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