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Rutinmässig screening med APTT är inte indicerad före operation: [Routine screening with APTT is not indicated before surgery
Sahlgrenska universitetssjukhuset, Göteborg, Sverige.
Sahlgrenska universitetssjukhuset, Göteborg, Sverige.
Karolinska universitetssjukhuset, Stockholm, Sverige.
Sahlgrenska universitetssjukhuset, Göteborg, Sverige.
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2022 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 119, article id 21240Article, review/survey (Refereed) Published
Abstract [en]

Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. The current literature does not support coagulation screening with APTT in routine perioperative bleeding assessment, as preoperative screening with APTT has a low sensitivity for detection of clinically significant bleeding disorder. While a comprehensive bleeding history is crucial, the APTT test should only be performed on patients with a history of increased bleeding tendency. The conclusion of this literature review is that patients with a negative bleeding history do not require routine screening with APTT prior to surgery, which, if implemented, would lead to a more cost-effective perioperative routine.

Abstract [sv]

APTT bör endast användas som screeningtest vid utredning av ökad blödningsbenägenhet.

APTT bör inte används rutinmässigt preoperativt som screeningtest för ökad blödningsrisk.

Normal APTT utesluter inte koagulationsrubbning.

Förlängd APTT är inte alltid relaterad till blödningsrisk.

Place, publisher, year, edition, pages
Sveriges Läkarförbund , 2022. Vol. 119, article id 21240
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Clinical Laboratory Medicine
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URN: urn:nbn:se:liu:diva-193505PubMedID: 35713306OAI: oai:DiVA.org:liu-193505DiVA, id: diva2:1754189
Available from: 2023-05-02 Created: 2023-05-02 Last updated: 2023-05-10Bibliographically approved

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Lindahl, Tomas

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Faculty of Medicine and Health SciencesDepartment of Clinical ChemistryDivision of Clinical Chemistry and Pharmacology
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Output format
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