Modeling Anaerobic Muscle Metabolism
Independent thesis Advanced level (degree of Magister), 20 points / 30 hpStudent thesis
Is it possible for a minimal model of anaerobic muscle contraction to describe measured data? There have been many models trying to describe separate parts of the human body with various results. In this thesis a model has been created to describe all the essential biochemical reactions of anaerobic muscle metabolism during contraction but with as few states and parameters as possible. A toolbox in Matlab was used for simulation and also for parameter estimation. The best model eventually got validated to see statistically how well it can describe the measured data. During the simulations an unnecessary assumption got revealed which helped us to understand the system better. The vision of a whole-body model may not be so far into the future as many think and the first step is to understand smaller biochemical systems like muscle contraction.
Place, publisher, year, edition, pages
Institutionen för systemteknik , 2008. , 72 p.
anaerobic muscle contraction, modeling, simulated annealing, Downhill simplex
IdentifiersURN: urn:nbn:se:liu:diva-11427ISRN: LiTH-ISY-EX--08/3789--SEOAI: oai:DiVA.org:liu-11427DiVA: diva2:17840
2008-03-14, Algoritmen, B-huset, 581 83, Linköpings Universitet, Linköping, 15:15
Tidefelt, HenrikCedersund, Gunnar