This chapter problematizes methodologies as a Euromodern/colonial epistemic framework. It reflects upon alternative decolonial instruments of analysis and broader practices of knowing and making sense of the world, which escape conventional methodological definitions. Methodology is seen as a specific classifying operation that is rationally limited by default and distorting for those who are not part of the Euromodern sameness. Revisiting decolonial and Indigenous texts while claiming to do away with modern/colonial methodologies or entering into an intense debate with them, this chapter argues that there is a corpus of core decolonial feminist texts (by scholars such as Chela Sandoval, Linda Tuhiwai Smith, Leanne Betasamosake Simpson, María Lugones, and Gloria Anzaldúa) that have engaged in dialogue with each other and, at different levels, with major methodological issues, and have come up with an open approach of relational experiential epistemic togetherness. The author addresses its main elements, including defamiliarization, decolonial hermeneutics, the corpopolitics and geopolitics of knowledge, being, sensing, the “Coatlicue state” and “la facultad” (as described in Gloria Anzaldúa’s Borderlands 1987). This chapter overall argues for emerging transversal decolonial agendas that advocate a shift towards imagining a redirected future that would come to life through the agency of changing communities and coalitions striving for re-existence.