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Active anterior rhinomanometry: A study on nasal airway resistance, paradoxical reactions to decongestion, and repeatability in healthy subjects
Ear Nose & Throat Clin, Sweden; Jonkoping Univ, Sweden; Lanssjukhuset Ryhov, Sweden.
Jonkoping Univ, Sweden.
Karolinska Inst, Sweden.
Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Clinical Neurophysiology. Jonkoping Univ, Sweden; Western Norway Univ Appl Sci, Norway.ORCID iD: 0000-0002-0433-0619
2023 (English)In: Laryngoscope Investigative Otolaryngology (LIO), E-ISSN 2378-8038, Vol. 8, no 5, p. 1136-1145Article in journal (Refereed) Published
Abstract [en]

ObjectivesAnterior active rhinomanometry (AAR) is widely used in Swedish routine clinical practice to decide if septoplasty is necessary. The scientific basis for the method needs to be strengthened. Therefore, the aims were to evaluate nasal airway resistance (NAR), paradoxical reactions to pharmacological decongestion, and test-retest characteristics of the Rhino-Comp (R) AAR in healthy subjects.MethodsA prospective longitudinal design was used. AAR was performed before and after decongestion at baseline and after >= 6 months on 60 healthy volunteers. The relationships between NAR, height, weight, BMI, sex, and allergic rhinitis were evaluated by regression analyses. Descriptive statistics were used to evaluate paradoxical reactions. Test-retest and repeatability characteristics were evaluated with intra-class coefficients (ICC), Cronbachs alpha, and standard error of measurementResultsNo statistically significant differences were found between genders or nasal cavity sides. NAR was statistically significantly related to height. Short- and long-term test-retest characteristics were good with ICC and Cronbachs alpha > .75. The minimal significant difference in NAR Log10V2 values between the two measurements was 0.11 and 0.09 (long- and short-term). Paradoxical reactions to pharmacological decongestion were rare, mostly weak, and not evidently reproducible.ConclusionIn this study, we report reference data for healthy subjects, test-retest capabilities, and the minimal relevant difference between two measurements for the Rhino-Comp (R) AAR, information that is vital and necessary for the appropriate use of AAR in clinical practice. An effective method for pharmacological decongestion is described and recommended for future studies and clinical practice. Paradoxical reactions to pharmacological decongestants exist but maybe without clinical significance.Level of EvidenceNA.

Place, publisher, year, edition, pages
WILEY , 2023. Vol. 8, no 5, p. 1136-1145
Keywords [en]
active anterior rhinomanometry; nasal airway resistance; paradoxical reaction; pharmacological decongestion; Rhino-Comp (R)
National Category
Physiotherapy
Identifiers
URN: urn:nbn:se:liu:diva-198666DOI: 10.1002/lio2.1157ISI: 001074826800001OAI: oai:DiVA.org:liu-198666DiVA, id: diva2:1806629
Note

Funding Agencies|The SNOT 22 was used under a license agreement with Washington University, USA

Available from: 2023-10-23 Created: 2023-10-23 Last updated: 2025-02-11

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