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Wet Organic Field Effect Transistor as DNA sensor
Linköping University, The Department of Physics, Chemistry and Biology.
2008 (English)Independent thesis Basic level (professional degree), 40 points / 60 hpStudent thesis
Abstract [en]

Label-free detection of DNA has been successfully demonstrated on field effect transistor (FET) based devices. Since conducting organic materials was discovered and have attracted more and more research efforts by their profound advantages, this work will focus on utilizing an organic field effect transistor (OFET) as DNA sensor.

An OFET constructed with a transporting fluidic channel, WetOFET, forms a fluid-polymer (active layer) interface where the probe DNA can be introduced. DNA hybridization and non-hybridization after injecting target DNA and non-target DNA were monitored by transistor characteristics. The Hysteresis area of transfer curve increased after DNA hybridization which may be caused by the increasing electrostatic screening induced by the increasing negative charge from target DNA. The different morphology of coating surface could also influence the OFET response.

Place, publisher, year, edition, pages
Institutionen för fysik, kemi och biologi , 2008. , 61 p.
Keyword [en]
Organic field effect transistor (OFET), Wet OFET, Poly(3-hexylthiophene) (P3HT), DNA sensor, Conjugated polymer, Micro fluidic channel.
National Category
Physical Sciences
URN: urn:nbn:se:liu:diva-11761ISRN: LITH-IFM-A-EX--08/1932--SEOAI: diva2:18191
2008-04-23, Plank, IFM (F building), Linköping University, Sweden, 15:15
Available from: 2008-06-23 Created: 2008-06-23

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