liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Shortened time to diagnosis for patients suspected of urinary bladder cancer managed in a standardized care pathway was associated with an improvement in tumour characteristics
Univ Goteborg, Sweden; NU Hosp Grp, Sweden; Univ Goteborg, Sweden.
Linköping University, Department of Biomedical and Clinical Sciences, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Urology in Östergötland.
Univ Goteborg, Sweden; Sahlgrens Univ Hosp, Sweden.
2024 (English)In: BJUI Compass, E-ISSN 2688-4526, Vol. 5, no 2, p. 261-268Article in journal (Refereed) Published
Abstract [en]

Objectives To evaluate whether the implementation of standardized care pathway (SCP) for patients with suspected urinary bladder cancer (UBC) was associated with changes in tumour characteristics. Additionally, the study aims to explore whether there was a shift in the selection of patients prioritized for immediate evaluation regarding suspicion of UBC.Materials and Methods The study included all patients diagnosed with UBC in the NU Hospital Group between 2010 and 2019. To evaluate changes associated with SCP, patients were divided into two diagnostic time periods, either before (2010-2015) or during (2016-2019) the implementation of the SCP. To evaluate which patients were prioritized for prompt evaluation within 13 days, logistic regression analysis was performed on all patients before and during SCP.Results Median time to transurethral resection of the tumour in urinary bladder (TURBT) decreased from 29 days (interquartile range [IQR] 16-48) before SCP to 12 days (IQR 8-19) during SCP (p < 0.001) with a clear break from 2016. The proportion of cT2 + tumours decreased during SCP from 26% to 20% (p = 0.035). In addition, tumours detected during SCP were smaller (p = 0.023), but with more multiple lesions (p = 0.055) and G3 tumours (p = 0.007). During SCP, there was no statistically significant difference between the groups of patients with TURBT within or after 13 days. In contrast, before SCP, a majority of the patients treated within 13 days had advanced tumours and were admitted from the emergency ward.Conclusions The implementation of an SCP for suspected UBC was associated with improved tumour characteristics. Interestingly, during SCP, there were no substantial differences in patients' or tumours' characteristics among those who underwent TURBT within or after 13 days. This indicates that the 13-day timeframe for TURBT might be prolonged, especially in less urgent cases in order to facilitate a prioritization of more severe cases with treatable disease.

Place, publisher, year, edition, pages
WILEY , 2024. Vol. 5, no 2, p. 261-268
Keywords [en]
bladder cancer; haematuria; resection of tumour in the urinary bladder; standardized care pathways; transurethral; trends
National Category
Surgery
Identifiers
URN: urn:nbn:se:liu:diva-200082DOI: 10.1002/bco2.301ISI: 001128054200001OAI: oai:DiVA.org:liu-200082DiVA, id: diva2:1827709
Note

Funding Agencies|Department of Research and Development, NU Hospital Group

Available from: 2024-01-15 Created: 2024-01-15 Last updated: 2024-11-21

Open Access in DiVA

fulltext(316 kB)3 downloads
File information
File name FULLTEXT01.pdfFile size 316 kBChecksum SHA-512
076a319ead5f322e782ec9aba5ee8a4b974064dae691c0cc884481d1edd25896b1d6edc665e7b47b04344e9b218f92d559f2957292f9fee0878cf7a0eaf223bc
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Jahnson, Staffan
By organisation
Division of Surgery, Orthopedics and OncologyFaculty of Medicine and Health SciencesDepartment of Urology in Östergötland
In the same journal
BJUI Compass
Surgery

Search outside of DiVA

GoogleGoogle Scholar
Total: 3 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 114 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf