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Segmentation of the Brain from MR Images
Linköping University, Department of Biomedical Engineering, Medical Informatics. Linköping University, The Institute of Technology.
2005 (English)Independent thesis Basic level (professional degree), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

KTH, Division of Neuronic Engineering, have a finite element model of the head. However, this model does not contain detailed modeling of the brain. This thesis project consists of finding a method to extract brain tissues from T1-weighted MR images of the head. The method should be automatic to be suitable for patient individual modeling.

A summary of the most common segmentation methods is presented and one of the methods is implemented. The implemented method is based on the assumption that the probability density function (pdf) of an MR image can be described by parametric models. The intensity distribution of each tissue class is modeled as a Gaussian distribution. Thus, the total pdf is a sum of Gaussians. However, the voxel values are also influenced by intensity inhomogeneities, which affect the pdf. The implemented method is based on the expectation-maximization algorithm and it corrects for intensity inhomogeneities. The result from the algorithm is a classification of the voxels. The brain is extracted from the classified voxels using morphological operations.

Place, publisher, year, edition, pages
Institutionen för medicinsk teknik , 2005. , 60 p.
Keyword [en]
MR images, automatic segmentation, voxel classification, intensity inhomogeneities, the expectation-maximization algorithm
National Category
Biomedical Laboratory Science/Technology
URN: urn:nbn:se:liu:diva-3568ISRN: LiTH-IMT/MI20-EX--05/402--SEOAI: diva2:20405
Subject / course
Medical Informatics
Available from: 2005-09-07 Created: 2005-09-07 Last updated: 2012-09-27

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