Sex differences in neuropeptide distribution in the rat brain
1999 (English)In: Peptides, ISSN 0196-9781, E-ISSN 1873-5169, Vol. 20, no 1, 81-86 p.Article in journal (Refereed) Published
We have investigated possible sex differences in the regional concentrations of neuropeptides in the rat brain. Immunoreactive neurotensin (NT), neurokinin A (NKA), galanin (GAL), calcitonin gene-related peptide (CGRP), substance P (SP) and neuropeptide Y (NPY) were measured by radioimmunoassay in frontal cortex, occipital cortex, hippocampus, striatum, hypothalamus and pituitary in male and female pre- and postpubertal rats. Sex differences were found for NPY (p < 0.001), NT (p < 0.01) and GAL (p < 0.05), in particular in hippocampus, striatum, hypothalamus and pituitary, but not for CGRP, SP and NKA. Results from analysis of neuropeptides in one sex may not be entirely applicable to the other.
Place, publisher, year, edition, pages
1999. Vol. 20, no 1, 81-86 p.
Sex differences, Neuropeptide Y, Neurotensin, Galanin, Hippocampus, Pituitary, Frontal cortex, Puberty
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-13441DOI: 10.1016/S0196-9781(98)00139-9OAI: oai:DiVA.org:liu-13441DiVA: diva2:20733