liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Visual Grading of 2D and 3D fMRI compared to image based descriptive measures
Linköping University, Department of Medical and Health Sciences, Radiology. Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Radiation Physics. Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Radiation Physics. Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Radiology. Linköping University, Faculty of Health Sciences.
Show others and affiliations
2010 (English)In: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 20, no 3, 714-724 p.Article in journal (Refereed) Published
Abstract [en]

A prerequisite for successful clinical use of functional Magnetic Resonance Imaging (fMRI) is the selection of an appropriate imaging sequence. In this paper, 2D and 3D fMRI sequences were compared using different image quality assessment methods. Descriptive image measures, such as activation volume and temporal signal-to-noise ratio (TSNR), were compared with results from Visual Grading Characteristics (VGC) analysis of the fMRI results. It was found that significant differences in activation volume and TSNR were not directly reflected by differences in VGC scores. The results suggest that better performance on descriptive image measures is not always an indicator of improved diagnostic quality of the fMRI results. In conclusion, in addition to descriptive image measures, it is important to include measures of diagnostic quality when comparing different fMRI data acquisition methods.

Place, publisher, year, edition, pages
Berlin / Heidelberg: Springer , 2010. Vol. 20, no 3, 714-724 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-17994DOI: 10.1007/s00330-009-1578-0ISI: 000274544800023PubMedID: 19727748OAI: oai:DiVA.org:liu-17994DiVA: diva2:213956
Note

The original publication is available at www.springerlink.com: Mattias Ragnehed, Olof Dahlqvist Leinhard, Johan Pihlsgård, Staffan Wirell, Hannibal Sökjer, Patrik Fägerstam, Bo Jiang, Örjan Smedby, Maria Engström and Peter Lundberg, Visual Grading of 2D and 3D fMRI compared to image based descriptive measures, 2010, European Radiology, (20), 3, 714-724. http://dx.doi.org/10.1007/s00330-009-1578-0 Copyright: Springer Science Business Media http://www.springerlink.com/

Available from: 2009-04-30 Created: 2009-04-30 Last updated: 2017-12-13Bibliographically approved
In thesis
1. Functional Magnetic Resonance Imaging for Clinical Diagnosis: Exploring and Improving the Examination Chain
Open this publication in new window or tab >>Functional Magnetic Resonance Imaging for Clinical Diagnosis: Exploring and Improving the Examination Chain
2009 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Functional Magnetic Resonance Imaging (fMRI) is a relatively new imaging technique, first reported in 1992, which enables mapping of brain functions with high spatial resolution. Functionally active areas are distinguished by a small signal increase mediated by changes in local blood oxygenation in response to neural activity. The ability to non-invasively map brain function and the large number of MRI scanners quickly made the method very popular, and fMRI have had a huge impact on the study of brain function, both in healthy and diseased subjects.

The most common clinical application of fMRI is pre-surgical mapping of brain functions in order to optimise surgical interventions. The clinical fMRI examination procedure can be divided into four integrated parts: (1) patient preparation, (2) image acquisition, (3) image analysis and (4) clinical decision. In this thesis, important aspects of all parts of the fMRI examination procedure are explored with the aim to provide recommendations and methods for prosperous clinical usage of the technique.

The most important results of the thesis were: (I) administration of low doses of diazepam to reduce anxiety did not invalidate fMRI mapping results of primary motor and language areas, (II) the choice of visual stimuli equipment can have severe impact on the mapping of visual areas, (III) three-dimensional fMRI imaging sequences did not perform better than two-dimensional imaging sequences, (IV) adaptive spatial filtering can improve the fMRI data analysis, (V) clinical decisions should not be based on activation results from a single statistical threshold.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2009. 73 p.
Series
Linköping University Medical Dissertations, ISSN 0345-0082 ; 1121
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
urn:nbn:se:liu:diva-18095 (URN)978-91-7393-645-3 (ISBN)
Public defence
2009-06-02, Majoren, Brigaden Restaurang & Konferens, Brigadgatan 17, 587 58 Linköping, Linköping, 09:15 (Swedish)
Opponent
Supervisors
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2014-10-02Bibliographically approved

Open Access in DiVA

fulltext(1203 kB)774 downloads
File information
File name FULLTEXT01.pdfFile size 1203 kBChecksum SHA-512
06cc0f1ec268cbbdcb928125ac1d69809a131d00509478487271e2f446762d4ad6c777bc50bf4de3af26ae29a9957ab740f14b4ded0b0f1bf53db016b2a600ca
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Ragnehed, MattiasDahlqvist Leinhard, OlofPihlsgård, JohanWirell, StaffanSökjer, HannibalFägerstam, PatrikJiang, BoSmedby, ÖrjanEngström, MariaLundberg, Peter

Search in DiVA

By author/editor
Ragnehed, MattiasDahlqvist Leinhard, OlofPihlsgård, JohanWirell, StaffanSökjer, HannibalFägerstam, PatrikJiang, BoSmedby, ÖrjanEngström, MariaLundberg, Peter
By organisation
RadiologyCenter for Medical Image Science and Visualization (CMIV)Faculty of Health SciencesRadiation PhysicsMDI - Interaction and Service Design Research GroupThe Institute of TechnologyPharmacologyDepartment of Medical and Health SciencesDepartment of Radiology in LinköpingDepartment of Radiation Physics
In the same journal
European Radiology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 774 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 534 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf