Factors related to fatigue in women and men with early rheumatoid arthritis: The Swedish TIRA study
2009 (English)In: Journal of Rehabilitation Medicine, ISSN 1650-1977, Vol. 41, no 11, 904-912 p.Article in journal (Refereed) Published
Objective: To study whether there are differences between women and men, with regard to the reported level of fatigue, and to explore the strength of the relations between fatigue and disease activity, pain, sleep disturbance, mental health, and activity limitation in early rheumatoid arthritis, and also to explore the consistency of such findings.
Design: Analyses and comparisons of cross-sectional data.
Subjects. 276 patients, 191 women and 85 men, with early rheumatoid arthritis were included.
Method: Patients were examined with respect to 28-joint count disease activity score, and disability variables reflecting pain, sleep disturbance, fatigue, mental health, and activity limitation, at follow-ups at one, two and three years after diagnosis.
Results: Women reported somewhat more fatigue than men. Fatigue was closely and rather consistently related to disease activity, pain and activity limitation, and also to mental health and sleep disturbance.
Conclusion: Although this study does not permit conclusions about causal directions, statistical relationships may be related to clinical conceptions about causation: When disease activity can be significantly reduced by pharmacological treatment, this may have a positive effect on fatigue. Specific treatment with respect to the mentioned disability aspects that are related to fatigue is also a clinically reasonable strategy.
Place, publisher, year, edition, pages
Uppsala, Sweden: FOUNDATION REHABILITATION INFORMATION , 2009. Vol. 41, no 11, 904-912 p.
Early rheumatoid arthritis, fatigue, sleep disturbance, sex
IdentifiersURN: urn:nbn:se:liu:diva-18108DOI: 10.2340/16501977-0444ISI: 000271102800008PubMedID: 19841842OAI: oai:DiVA.org:liu-18108DiVA: diva2:214760