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The influence of Ca2+ and Nitroprusside on the opening kinematics of the mitral valve
Linköping University, Department of Biomedical Engineering.
2006 (English)Independent thesis Basic level (professional degree), 20 points / 30 hpStudent thesis
Abstract [en]

During a cardiac cycle the cardiac walls change between contracted and relaxed and the valves open and close in response to pressure changes. This master thesis is a study of the changes in heart movement pattern caused by intravenous injections of Ca2+ or Nitroprusside. At Stanford University radiopaque markers have been surgically implanted in the walls and in the mitral valve of ovine hearts and 3D coordinates for each marker have been constantly measured during the cardiac cycle. By using MatLab, the volume and pressure of the left ventricle and several parameters related to the opening kinematics of the mitral valve have been analyzed. The results show, among others, that both Ca2+ and Nitroprusside reduce the volume and pressure of the left ventricle and that both substances decrease the size of the mitral annular ring. It was also shown that Ca2+ delays the opening of the mitral valve.

Place, publisher, year, edition, pages
Institutionen för medicinsk teknik , 2006. , 57 p.
Keyword [en]
mitral valve, opening, calcium, nitroprusside
National Category
Medical Laboratory and Measurements Technologies
Identifiers
URN: urn:nbn:se:liu:diva-6226ISRN: LITH-IMT/BMS20-EX--06/417--SEOAI: oai:DiVA.org:liu-6226DiVA: diva2:21709
Presentation
2006-01-20, IMT 1, Linköpings Universitet, SE-58183, Linköping, 13:15
Uppsok
teknik
Supervisors
Examiners
Available from: 2006-04-05 Created: 2006-04-05

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Department of Biomedical Engineering
Medical Laboratory and Measurements Technologies

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CiteExportLink to record
Permanent link

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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
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  • asciidoc
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