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Weight Loss, Body Fat Mass, and Leptin in Parkinsons Disease
Linköping University, Department of Medicine and Health Sciences, Nursing Science. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medicine and Health Sciences, Internal Medicine . Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre for Medicine, Department of Endocrinology and Gastroenterology UHL.
Linköping University, Department of Clinical and Experimental Medicine, Geriatric . Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Department of Geriatric Medicine.
2009 (English)In: MOVEMENT DISORDERS, ISSN 0885-3185, Vol. 24, no 6, 885-890 p.Article in journal (Refereed) Published
Abstract [en]

Weight loss is a common problem in Parkinsons disease (PD), but the causative mechanisms behind this weight loss are unclear. We compared 2( PD patients with sex and age matched healthy controls. Examinations were repeated at baseline, after one and after two years. Body fat mass was measured by Dual X-ray Absorptiometry (DXA). Seventy three per cent of the PD patients lost body weight. Loss of body fat mass constituted a considerable part of the loss of body weight. In the patients who lost weight, serum leptin levels were lower than in those who did not lose weight. The relationship between low body fat mass and low leptin levels seems to be relevant, at least for female PD patients. It is reasonable to believe that low leptin levels in these patients could be secondary to the decreased body fat mass.

Place, publisher, year, edition, pages
2009. Vol. 24, no 6, 885-890 p.
Keyword [en]
Parkinsons disease, body weight, body fat mass, leptin
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-18270DOI: 10.1002/mds.22466OAI: oai:DiVA.org:liu-18270DiVA: diva2:217841
Available from: 2009-05-16 Created: 2009-05-15 Last updated: 2009-08-19

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Lorefält, BirgittaToss, GöranGranerus, Ann-Kathrine

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Nursing ScienceFaculty of Health SciencesInternal Medicine Department of Endocrinology and Gastroenterology UHLGeriatric Department of Geriatric Medicine
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CiteExportLink to record
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  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
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  • Other style
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Language
  • de-DE
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  • en-US
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  • sv-SE
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