Investigation of transmural cardiac and fiber strain in ischemic and non-ischemic tissue during diastole
Independent thesis Basic level (professional degree), 20 points / 30 hpStudent thesis
The cardiac wall has complex three-dimensional fiber structures and mechanical properties that enable the heart to efficiently pump the blood through the body. By studying the myocardial strains induced during diastole, information about the pumping performance of the heart and what mechanisms that are responsible for this effective blood filling, can be achieved. Two different computation methods for myocardial strain, both based on data acquired from marker technique, were compared using a theoretical cylinder model. The non-homogeneous polynomial fitting method yielded higher accuracy than a homogeneous tetrahedron method, and was further used to investigate cardiac and fiber strains at different wall depths and myocardial regions in normal and ischemic ovine hearts. Large spatial and regional variations were found, as well as alterations, conveyed by ischemic conditions, of fiber mechanisms responsible for the circumferential expansion and wall thinning during diastole.
Place, publisher, year, edition, pages
Institutionen för medicinsk teknik , 2006. , 81 p.
strain, cardiac, fiber, transmural, ischemic, tensor, markers
Medical Laboratory and Measurements Technologies
IdentifiersURN: urn:nbn:se:liu:diva-7955ISRN: LiTH-IMT/BMS20-EX--06/438--SEOAI: oai:DiVA.org:liu-7955DiVA: diva2:22852
2006-12-14, IMT1, IMT, Linköping, 10:15