Sagittal abdominal diameter and waist circumference as markers of early organ damage in patients with Type 2 diabetes
2011 (English)In: Journal of Clinical Metabolism & Diabetes, Vol. 2, no 1Article in journal (Refereed) Published
Aims: In a cohort of 465 patients with Type 2 diabetes aged 55-66 years the associationbetween the anthropometric measures: Waist circumference (WC) and Sagittal abdominaldiameter (SAD) versus subclinical cardiovascular organ damage by measuring Pulse wavevelocity (PWV) and Left ventricular mass index (LVMI) was studied.
Methods: Blood pressure, weight, height and WC were measured within primary care. SADwas measured by using standardized calliper equipment. Blood samples were taken foranalysis of HbA1c and serum lipids. LVMI was measured by M-mode echocardiography.Aortic PWV was measured by applanation tonometry (Sphygmocor®) over the carotid andfemoral arteries.
Results: There were significant correlations between aortic PWV and WC (r=0.23; p<0.01)and SAD (r=0.25; p<0.01). LVMI was also correlated to WC (r=0.26; p<0.01) and SAD(r=0.25; p<0.01). When analysed in a multiple regression model, SAD and WC were bothassociated with PWV and LVMI, independently of age, sex, systolic blood pressure, serumlipids and HbA1c.
Conclusion: This study shows that abdominal obesity, measured either with WC or SAD, is afeasible risk assessment tool for early subclinical organ damage in patients who have alreadydeveloped Type 2 diabetes.
Place, publisher, year, edition, pages
San Lucas Medical , 2011. Vol. 2, no 1
type 2 diabetes, obesity, pulse wave velocity, left ventricular mass
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-20579OAI: oai:DiVA.org:liu-20579DiVA: diva2:235280