On MRI turbulence quantification
2009 (English)In: Magnetic Resonance Imaging, ISSN 0730-725X, E-ISSN 1873-5894, Vol. 27, no 7, 913-922 p.Article in journal (Refereed) Published
Turbulent flow, characterized by velocity fluctuations, accompanies many forms of cardiovascular disease and may contribute to their progression and hemodynamic consequences. Several studies have investigated the effects of turbulence on the magnetic resonance imaging (MRI) signal. Quantitative MRI turbulence measurements have recently been shown to have great potential for application both in human cardiovascular flow and in engineering flow. In this article, potential pitfalls and sources of error in MRI turbulence measurements are theoretically and numerically investigated. Data acquisition strategies suitable for turbulence quantification are outlined. The results show that the sensitivity of MRI turbulence measurements to intravoxel mean velocity variations is negligible, but that noise may degrade the estimates if the turbulence encoding parameter is set improperly. Different approaches for utilizing a given amount of scan time were shown to influence the dynamic range and the uncertainty in the turbulence estimates due to noise. The findings reported in this work may be valuable for both in vitro and in vivo studies employing MRI methods for turbulence quantification.
Place, publisher, year, edition, pages
2009. Vol. 27, no 7, 913-922 p.
Turbulence quantification, Turbulent flow, Phase-contrast magnetic resonance imaging, Constriction, Numerical flow phantom
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-20746DOI: 10.1016/j.mri.2009.05.004ISI: 000269613000004OAI: oai:DiVA.org:liu-20746DiVA: diva2:235967
Original Publication: Petter Dyverfeldt, Roland Gårdhagen, Andreas Sigfridsson, Matts Karlsson and Tino Ebbers, On MRI turbulence quantification, 2009, MAGNETIC RESONANCE IMAGING, (27), 7, 913-922. http://dx.doi.org/10.1016/j.mri.2009.05.004 Copyright: Elsevier Science B.V., Amsterdam. http://www.elsevier.com/2009-09-182009-09-182015-10-08