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The physical performance of different x-ray contrast agents: calculations using a Monte Carlo model of the imaging chain
Linköping University, Department of Medicine and Health Sciences, Radiation Physics . Linköping University, Center for Medical Image Science and Visualization, CMIV. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Radiation Physics. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0003-3352-8330
n/a.
Linköping University, Department of Medicine and Care, Radiation Physics. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0003-0209-498X
n/a.
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1995 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 40, no 7, 1209-1224 p.Article in journal (Refereed) Published
Abstract [en]

A Monte Carlo computational model of the imaging chain has been used to investigate the performance of X-ray contrast agents with atomic number, Z, 53<or=Z<or=90 with respect to physical image quality descriptors (contrast and signal to noise ratio, SNR) and patient mean absorbed dose. Contrast agents of equal molar concentrations were used within a water slab (simulating the patient). The imaging conditions were chosen to represent adult and paediatric examinations. For all tube potentials studied (40-140 kV), the contrast agents with the highest atomic numbers (bismuth and thorium) gave the highest contrast. In analogue screen-film imaging, several other contrast agents could produce a higher image contrast than iodine in a limited range of tube potentials. This advantage could alternatively be effected as a reduced amount of administered contrast agent, or as a reduced mean absorbed dose in the patient. In digital imaging, a lower mean absorbed dose for a constant SNR than that with iodine can be achieved for ranges of tube potentials and contrast agents. Bismuth and thorium yield a lower dose than iodine at all studied tube potentials. Gadolinium and erbium could alternatively be used at a broad range of tube potentials above 90 kV with a dose penalty of only 5-20%.

Place, publisher, year, edition, pages
1995. Vol. 40, no 7, 1209-1224 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-20936DOI: 10.1088/0031-9155/40/7/005OAI: oai:DiVA.org:liu-20936DiVA: diva2:236835
Available from: 2009-09-25 Created: 2009-09-25 Last updated: 2017-12-13

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Sandborg, MichaelAlm Carlsson, Gudrun

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Radiation Physics Center for Medical Image Science and Visualization, CMIVDepartment of Radiation PhysicsFaculty of Health SciencesRadiation Physics
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