The physical performance of different x-ray contrast agents: calculations using a Monte Carlo model of the imaging chain
1995 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, Vol. 40, no 7, 1209-1224 p.Article in journal (Refereed) Published
A Monte Carlo computational model of the imaging chain has been used to investigate the performance of X-ray contrast agents with atomic number, Z, 53<or=Z<or=90 with respect to physical image quality descriptors (contrast and signal to noise ratio, SNR) and patient mean absorbed dose. Contrast agents of equal molar concentrations were used within a water slab (simulating the patient). The imaging conditions were chosen to represent adult and paediatric examinations. For all tube potentials studied (40-140 kV), the contrast agents with the highest atomic numbers (bismuth and thorium) gave the highest contrast. In analogue screen-film imaging, several other contrast agents could produce a higher image contrast than iodine in a limited range of tube potentials. This advantage could alternatively be effected as a reduced amount of administered contrast agent, or as a reduced mean absorbed dose in the patient. In digital imaging, a lower mean absorbed dose for a constant SNR than that with iodine can be achieved for ranges of tube potentials and contrast agents. Bismuth and thorium yield a lower dose than iodine at all studied tube potentials. Gadolinium and erbium could alternatively be used at a broad range of tube potentials above 90 kV with a dose penalty of only 5-20%.
Place, publisher, year, edition, pages
1995. Vol. 40, no 7, 1209-1224 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-20936DOI: 10.1088/0031-9155/40/7/005OAI: oai:DiVA.org:liu-20936DiVA: diva2:236835