Randomised clinical trials and evidence-based general dentistry
2004 (English)Doctoral thesis, comprehensive summary (Other academic)
A growing number of scientific publications and new treatment modalities have increased the difficulties of keeping up to date with the latest research evidence in clinical practice. Therefore, evidence-based dentistry and medicine (EBDM) has evolved as an attempt to summarise current best evidence.
The overall aim of this thesis was to study the availability and the methodological quality of randomised controlled trials (RCTs) in dental (RCT-Ds) and medical (RCT-Ms) research, and publications describing epidemiological registration methods of dental caries. It also examines the applicability of evidence-based methods to general dental practice.
The most important findings were that the armual number of publications in dental research showed a decreasing trend from 1969 to 1999, whereas medical research increased. The armual number of clinical trials (CTs), meta-analyses and RCTs increased, but represented just a fraction of all publications in both dental and medical research. Medical subject heading (MeSH) searches provided an overall adequate method for rapid location of RCT-Ds on Medline for most areas of dental research. The quality of RCT-Ds and RCT-Ms were generally inadequate. There was no correlation between the quality of RCTs and Journal Impact Factor. The armual number of publications, CTs and RCTs in periodontal research (RCT-Ps) increased during 1980-2000. A few clinical research areas dominated the RCT-Ps. Most of the RCT-Ps were published in just two different dental journals. Validation methodology in publications describing epidemiological methods for registering dental caries was inadequate according to EBDM recommendations and needs to be improved.
Place, publisher, year, edition, pages
Linköping: Linköpings universitet , 2004. , 57 p.
Linköping University Medical Dissertations, ISSN 0345-0082 ; 865
Dental care, dental research, epidemiological methods, evidence-based medicine, Medline, randomized controlled trials, validity
IdentifiersURN: urn:nbn:se:liu:diva-22686Local ID: 1978ISBN: 91-7373-839-5OAI: oai:DiVA.org:liu-22686DiVA: diva2:242999
2004-11-12, Aulan, Hälsans Hus, Hälsouniversitetet, Linköping, 13:00 (Swedish)
Klinge, Björn, Professor
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